C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosyl-DNA phosphodiesterase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021177 Tdp1 10090 + 12:99884517-99955219 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021594 Tdp1-201 99891173-99955214 protein_coding
  ENSMUST00000125639 Tdp1-004 99884534-99887687 processed_transcript
  ENSMUST00000126424 Tdp1-005 99911648-99912579 retained_intron
  ENSMUST00000128739 Tdp1-006 99914006-99955219 retained_intron
  ENSMUST00000137653 Tdp1-003 99886484-99891338 protein_coding
  ENSMUST00000151019 Tdp1-002 99884517-99937362 retained_intron
  ENSMUST00000153627 Tdp1-001 99884537-99955219 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021594ENSMUST00000126424ENSMUST00000128739ENSMUST00000151019ENSMUST00000153627
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021594 2.303±0.00 1.127±0.42 N/A 1.199±0.00 1.831±0.93 1.802±0.00 N/A 0.520±0.00 N/A N/A 0.726±0.59 3.264±1.24 5.663±3.64 2.379±0.00
ENSMUST00000126424 N/A N/A N/A 2.742±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000128739 2.254±0.23 1.243±0.31 2.193±0.00 3.383±0.00 2.147±0.26 1.421±0.70 1.795±0.18 2.583±0.47 0.841±0.31 2.449±0.46 0.937±0.04 4.749±0.04 5.278±1.30 10.262±0.00
ENSMUST00000151019 N/A N/A N/A 0.994±0.00 N/A N/A N/A N/A N/A N/A 0.086±0.00 N/A N/A N/A
ENSMUST00000153627 4.047±1.02 1.916±0.27 3.729±1.06 13.261±1.00 2.307±0.55 1.592±0.63 1.426±0.11 2.241±0.57 5.639±5.22 3.096±1.15 1.164±0.08 6.524±1.80 7.066±1.96 29.049±13.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005C6 CIL_0005C6_0002 CGP 12:99717531-99955219
CIL_0001TZ CIL_0001TZ_0002 CGP 12:99884517-100062682

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000012 IMP single strand break repair
GO:0003690 IEA double-stranded DNA binding
GO:0003697 IEA single-stranded DNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006281 IMP DNA repair
GO:0006302 IEA double-strand break repair
GO:0017005 IEA 3'-tyrosyl-DNA phosphodiesterase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073866 tdp1 tyrosyl-DNA phosphodiesterase 1 protein_coding Danio_rerio
ENSG00000042088 TDP1 tyrosyl-DNA phosphodiesterase 1 protein_coding Homo_sapiens

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