C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tyrosyl-DNA phosphodiesterase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000153627 Tdp1-001 ENSMUSG00000021177 10090 + 12:99884537-99955219 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000153627
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000153627 4.047±1.02 1.916±0.27 3.729±1.06 13.261±1.00 2.307±0.55 1.592±0.63 1.426±0.11 2.241±0.57 5.639±5.22 3.096±1.15 1.164±0.08 6.524±1.80 7.066±1.96 29.049±13.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005C6 CIL_0005C6_0002 CGP 12:99717531-99955219
CIL_0001TZ CIL_0001TZ_0002 CGP 12:99884517-100062682

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000012 IMP single strand break repair
GO:0003690 IEA double-stranded DNA binding
GO:0003697 IEA single-stranded DNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006281 IMP DNA repair
GO:0006302 IEA double-strand break repair
GO:0017005 IEA 3'-tyrosyl-DNA phosphodiesterase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000335725 TDP1-001 protein_coding Homo_sapiens 0 1557
ENST00000393452 TDP1-003 protein_coding Homo_sapiens 0 1373
ENST00000393454 TDP1-006 protein_coding Homo_sapiens 0 1561
ENST00000545686 TDP1-004 nonsense_mediated_decay Homo_sapiens 0 704
ENST00000553617 TDP1-010 protein_coding Homo_sapiens 0 676
ENST00000554180 TDP1-009 protein_coding Homo_sapiens 0 614
ENST00000554976 TDP1-002 nonsense_mediated_decay Homo_sapiens 0 894
ENST00000555178 TDP1-005 nonsense_mediated_decay Homo_sapiens 0 1014
ENST00000555565 TDP1-015 processed_transcript Homo_sapiens 0 351
ENST00000555880 TDP1-007 protein_coding Homo_sapiens 0 1373
ENST00000556063 TDP1-008 protein_coding Homo_sapiens 0 664
ENST00000557782 TDP1-016 nonsense_mediated_decay Homo_sapiens 1.96182e-44 182

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