C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: estrogen related receptor, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021255 Esrrb 10090 + 12:86361117-86521628 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021680 Esrrb-006 86421883-86519800 protein_coding
  ENSMUST00000110203 Esrrb-003 86421644-86515522 protein_coding
  ENSMUST00000110204 Esrrb-002 86421644-86521625 protein_coding
  ENSMUST00000116402 Esrrb-001 86361117-86521628 protein_coding
  ENSMUST00000136464 Esrrb-004 86504409-86509967 processed_transcript
  ENSMUST00000167891 Esrrb-005 86470117-86519065 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021680ENSMUST00000110203ENSMUST00000110204ENSMUST00000116402ENSMUST00000136464ENSMUST00000167891
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021680 0.029±0.00 0.049±0.01 0.004±0.00 N/A N/A 0.018±0.00 N/A N/A N/A 0.024±0.00 0.472±0.00 0.256±0.03 N/A N/A
ENSMUST00000110203 N/A 0.096±0.02 N/A N/A 0.951±0.00 N/A N/A N/A 0.116±0.00 0.022±0.00 N/A N/A N/A N/A
ENSMUST00000110204 0.036±0.02 0.033±0.01 0.007±0.00 2.087±1.53 0.524±0.12 N/A 2.157±0.31 7.323±1.34 0.139±0.08 0.063±0.01 1.066±0.41 0.249±0.09 1.220±1.18 1.571±0.00
ENSMUST00000116402 0.016±0.00 N/A N/A N/A 0.204±0.03 0.067±0.04 4.504±0.47 1.203±0.43 0.042±0.00 0.150±0.01 0.500±0.34 0.375±0.12 0.773±0.00 N/A
ENSMUST00000136464 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.200±0.61 N/A N/A
ENSMUST00000167891 0.096±0.00 0.066±0.00 0.006±0.00 N/A N/A 0.190±0.06 N/A N/A 0.042±0.00 0.036±0.00 N/A 0.648±0.00 N/A 1.791±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007M1 CIL_0007M1_0002 UCNEbase 12:86115809-86636147
CIL_0005O2 CIL_0005O2_0002 CGP 12:86241890-86521628
CIL_0003P4 CIL_0003P4_0002 CGP 12:86361117-86692091

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001701 IMP in utero embryonic development
GO:0001831 IMP trophectodermal cellular morphogenesis
GO:0001834 IMP trophectodermal cell proliferation
GO:0001892 IMP embryonic placenta development
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003713 IDA transcription coactivator activity
GO:0005496 IEA steroid binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0019827 IMP stem cell maintenance
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 ISS sequence-specific DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040151 esrrb estrogen-related receptor beta protein_coding Danio_rerio
ENSG00000119715 ESRRB estrogen-related receptor beta protein_coding Homo_sapiens

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