C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: orthodenticle homolog 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021848 Otx2 10090 - 14:48657679-48667644 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000118578 Otx2-001 48657679-48665246 protein_coding
  ENSMUST00000119070 Otx2-002 48658171-48667513 protein_coding
  ENSMUST00000119739 Otx2-008 48661408-48665521 protein_coding
  ENSMUST00000122009 Otx2-003 48658171-48662872 protein_coding
  ENSMUST00000133479 Otx2-006 48661358-48667508 protein_coding
  ENSMUST00000135279 Otx2-005 48658916-48661932 protein_coding
  ENSMUST00000144465 Otx2-007 48659305-48667508 protein_coding
  ENSMUST00000152018 Otx2-004 48658953-48667644 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLiverTestisENSMUST00000118578ENSMUST00000119070ENSMUST00000119739ENSMUST00000122009ENSMUST00000135279
Transcript ID Brain Liver Testis
ENSMUST00000118578 3.496±2.63 N/A 0.016±0.00
ENSMUST00000119070 3.471±2.22 N/A 0.020±0.00
ENSMUST00000119739 N/A 0.030±0.00 N/A
ENSMUST00000122009 N/A 0.019±0.00 N/A
ENSMUST00000135279 N/A N/A 0.107±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007P7 CIL_0007P7_0002 UCNEbase 14:48393330-49089945
CIL_00083W CIL_00083W_0002 VISTA 14:48407510-49011185
CIL_000602 CIL_000602_0003 CGP 14:48446128-48667644
CIL_000869 CIL_000869_0002 VISTA 14:48499224-49101650
CIL_0009BX CIL_0009BX_0002 VISTA 14:48514603-49116118
CIL_000822 CIL_000822_0002 VISTA 14:48552340-49156614
CIL_0005ZZ CIL_0005ZZ_0003 CGP 14:48657679-49066653

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001708 IMP cell fate specification
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006461 IEA protein complex assembly
GO:0007411 IEA axon guidance
GO:0007417 IMP central nervous system development
GO:0007492 IGI endoderm development
GO:0009887 IMP organ morphogenesis
GO:0009952 IGI anterior/posterior pattern specification
GO:0009953 IMP dorsal/ventral pattern formation
GO:0022037 IGI metencephalon development
GO:0030154 IMP cell differentiation
GO:0030182 IMP neuron differentiation
GO:0030426 IEA growth cone
GO:0030900 IMP forebrain development
GO:0030901 IMP midbrain development
GO:0032525 IMP somite rostral/caudal axis specification
GO:0042472 IGI inner ear morphogenesis
GO:0042706 IMP eye photoreceptor cell fate commitment
GO:0043234 IEA protein complex
GO:0043565 IEA sequence-specific DNA binding
GO:0045165 IMP cell fate commitment
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048663 IMP neuron fate commitment
GO:0048664 IMP neuron fate determination
GO:0048852 IGI diencephalon morphogenesis
GO:0048856 IGI anatomical structure development
GO:0090009 IMP primitive streak formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011235 otx2 orthodenticle homolog 2 protein_coding Danio_rerio
ENSG00000165588 OTX2 orthodenticle homeobox 2 protein_coding Homo_sapiens

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