C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: orthodenticle homolog 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000119070 Otx2-002 ENSMUSG00000021848 10090 - 14:48658171-48667513 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainTestisENSMUST00000119070
Transcript ID Brain Testis
ENSMUST00000119070 3.471±2.22 0.020±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007P7 CIL_0007P7_0002 UCNEbase 14:48393330-49089945
CIL_00083W CIL_00083W_0002 VISTA 14:48407510-49011185
CIL_000602 CIL_000602_0003 CGP 14:48446128-48667644
CIL_000869 CIL_000869_0002 VISTA 14:48499224-49101650
CIL_0009BX CIL_0009BX_0002 VISTA 14:48514603-49116118
CIL_000822 CIL_000822_0002 VISTA 14:48552340-49156614
CIL_0005ZZ CIL_0005ZZ_0003 CGP 14:48657679-49066653

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001708 IMP cell fate specification
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006461 IEA protein complex assembly
GO:0007411 IEA axon guidance
GO:0007417 IMP central nervous system development
GO:0007492 IGI endoderm development
GO:0009887 IMP organ morphogenesis
GO:0009952 IGI anterior/posterior pattern specification
GO:0009953 IMP dorsal/ventral pattern formation
GO:0022037 IGI metencephalon development
GO:0030154 IMP cell differentiation
GO:0030182 IMP neuron differentiation
GO:0030426 IEA growth cone
GO:0030900 IMP forebrain development
GO:0030901 IMP midbrain development
GO:0032525 IMP somite rostral/caudal axis specification
GO:0042472 IGI inner ear morphogenesis
GO:0042706 IMP eye photoreceptor cell fate commitment
GO:0043234 IEA protein complex
GO:0045165 IMP cell fate commitment
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048663 IMP neuron fate commitment
GO:0048664 IMP neuron fate determination
GO:0048852 IGI diencephalon morphogenesis
GO:0048856 IGI anatomical structure development
GO:0090009 IMP primitive streak formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000339475 OTX2-001 protein_coding Homo_sapiens 0 2302
ENST00000408990 OTX2-007 protein_coding Homo_sapiens 0 1389
ENST00000554559 OTX2-004 protein_coding Homo_sapiens 0 508
ENST00000554788 OTX2-005 protein_coding Homo_sapiens 0 881
ENST00000554845 OTX2-006 protein_coding Homo_sapiens 0 1212
ENST00000555006 OTX2-002 protein_coding Homo_sapiens 0 1417
ENST00000555804 OTX2-003 protein_coding Homo_sapiens 0 809

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