C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box and leucine-rich repeat protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022124 Fbxl3 10090 - 14:103080239-103099566 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022720 Fbxl3-001 103080239-103099554 protein_coding
  ENSMUST00000123043 Fbxl3-005 103089452-103095748 protein_coding
  ENSMUST00000127113 Fbxl3-006 103083105-103089817 retained_intron
  ENSMUST00000132004 Fbxl3-003 103081684-103098975 protein_coding
  ENSMUST00000144141 Fbxl3-004 103089414-103099566 protein_coding
  ENSMUST00000145693 Fbxl3-002 103081034-103098999 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022720ENSMUST00000123043ENSMUST00000127113ENSMUST00000132004ENSMUST00000144141ENSMUST00000145693
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022720 5.321±2.99 8.436±3.09 N/A 3.028±0.93 5.801±2.19 9.831±4.25 3.114±1.34 6.103±1.90 2.808±0.48 14.267±1.44 1.684±0.12 12.170±3.33 2.543±0.86 1.880±0.27
ENSMUST00000123043 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 35.673±0.00 N/A 8.010±0.00
ENSMUST00000127113 23.795±3.91 14.851±3.83 N/A 10.974±0.55 21.986±7.16 22.946±1.15 13.369±0.27 16.864±4.10 7.784±1.56 28.944±0.88 N/A 17.093±3.31 8.961±0.00 5.831±0.40
ENSMUST00000132004 4.155±0.00 N/A N/A 8.502±0.00 N/A N/A 3.511±0.41 3.943±0.52 N/A N/A 3.027±0.00 7.126±0.00 5.065±1.11 3.273±0.00
ENSMUST00000144141 N/A 10.933±0.00 N/A N/A N/A 12.979±0.00 N/A 12.375±0.00 N/A N/A N/A 13.616±2.05 N/A 6.262±0.48
ENSMUST00000145693 3.036±0.00 6.550±0.00 12.342±0.57 7.154±0.76 4.315±1.90 6.229±2.30 1.911±0.11 4.097±0.00 4.907±2.97 8.851±0.00 6.630±3.37 10.762±4.75 9.142±3.17 1.956±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004PQ CIL_0004PQ_0003 CGP 14:103070216-103099566
CIL_00004B CIL_00004B_0002 CGP 14:103080239-103346814

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 IDA cytosol
GO:0016567 IEA protein ubiquitination
GO:0019005 ISS SCF ubiquitin ligase complex
GO:0031146 ISS SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 IMP protein destabilization
GO:0042752 IMP regulation of circadian rhythm
GO:0043153 IMP entrainment of circadian clock by photoperiod
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021882 fbxl3b F-box and leucine-rich repeat protein 3b protein_coding Danio_rerio
ENSDARG00000078003 fbxl3a F-box and leucine-rich repeat protein 3a protein_coding Danio_rerio
ENSG00000005812 FBXL3 F-box and leucine-rich repeat protein 3 protein_coding Homo_sapiens

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