C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LPS-induced TN factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022500 Litaf 10090 - 16:10959275-11066157 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023143 Litaf-001 10959275-10993121 protein_coding
  ENSMUST00000117360 Litaf-002 10960824-10975579 protein_coding
  ENSMUST00000140170 Litaf-003 10966331-10993071 retained_intron
  ENSMUST00000162323 Litaf-004 10963343-11066157 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023143ENSMUST00000117360
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023143 49.514±15.42 17.865±3.38 16.351±0.87 3.904±2.38 40.396±6.50 67.678±16.54 7.474±3.16 26.099±1.89 21.721±10.65 41.621±5.82 1.504±0.39 45.315±17.28 34.390±19.95 4.714±1.95
ENSMUST00000117360 26.338±3.03 62.933±2.51 N/A 1.501±0.00 39.437±4.14 113.404±21.31 5.219±0.00 13.301±3.20 28.944±10.78 17.410±4.38 N/A 49.852±12.19 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043Q CIL_00043Q_0002 CGP 16:10835059-11066157
CIL_0007HQ CIL_0007HQ_0003 CGP 16:10959275-11074983

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001817 IMP regulation of cytokine production
GO:0004871 ISS signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005765 ISO lysosomal membrane
GO:0005794 ISS Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0007165 IEA signal transduction
GO:0007568 IEA aging
GO:0032496 IMP response to lipopolysaccharide
GO:0042347 IMP negative regulation of NF-kappaB import into nucleus
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0050699 ISS WW domain binding
GO:0071222 IMP cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052666 litaf lipopolysaccharide-induced TNF factor protein_coding Danio_rerio
ENSG00000189067 LITAF lipopolysaccharide-induced TNF factor protein_coding Homo_sapiens

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