C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023030 Slc11a2 10090 - 15:100387898-100425072 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023774 Slc11a2-001 100387898-100423055 protein_coding
  ENSMUST00000123461 Slc11a2-005 100406306-100425072 protein_coding
  ENSMUST00000124324 Slc11a2-009 100397594-100403243 protein_coding
  ENSMUST00000136168 Slc11a2-004 100408140-100422969 nonsense_mediated_decay
  ENSMUST00000138843 Slc11a2-002 100392563-100423002 protein_coding
  ENSMUST00000140535 Slc11a2-008 100397782-100403422 retained_intron
  ENSMUST00000154331 Slc11a2-003 100409269-100424214 protein_coding
  ENSMUST00000154676 Slc11a2-006 100410114-100424092 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023774ENSMUST00000138843
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023774 12.105±2.63 26.801±5.05 7.673±1.16 7.890±0.55 10.855±3.12 14.789±2.40 7.354±0.42 19.202±0.78 12.401±10.12 11.567±0.31 4.477±1.43 19.461±7.97 6.994±3.05 3.986±1.93
ENSMUST00000138843 5.268±0.34 8.573±1.39 2.156±0.22 5.034±2.54 2.992±0.38 4.080±0.29 3.607±0.37 15.819±4.10 8.423±2.16 6.278±0.61 4.758±0.69 4.383±1.56 7.645±3.75 6.030±2.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007B4 CIL_0007B4_0002 CGP 15:100364542-100425072

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000041 IEA transition metal ion transport
GO:0001666 IEA response to hypoxia
GO:0003032 IEA detection of oxygen
GO:0005375 IEA copper ion transmembrane transporter activity
GO:0005381 IDA iron ion transmembrane transporter activity
GO:0005384 IEA manganese ion transmembrane transporter activity
GO:0005385 IEA zinc ion transmembrane transporter activity
GO:0005506 IEA iron ion binding
GO:0005507 IEA copper ion binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005764 IEA lysosome
GO:0005765 IEA lysosomal membrane
GO:0005768 IDA endosome
GO:0005769 IDA early endosome
GO:0005770 IEA late endosome
GO:0005773 IEA vacuole
GO:0005802 IEA trans-Golgi network
GO:0005886 IDA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0005903 IDA brush border
GO:0006778 IMP porphyrin-containing compound metabolic process
GO:0006779 IMP porphyrin-containing compound biosynthetic process
GO:0006783 IMP heme biosynthetic process
GO:0006824 IDA cobalt ion transport
GO:0006825 IEA copper ion transport
GO:0006826 IDA iron ion transport
GO:0006828 IEA manganese ion transport
GO:0006878 IEA cellular copper ion homeostasis
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007611 IMP learning or memory
GO:0008270 IEA zinc ion binding
GO:0009986 IDA cell surface
GO:0010039 IEA response to iron ion
GO:0010042 IEA response to manganese ion
GO:0010288 IEA response to lead ion
GO:0012505 IDA endomembrane system
GO:0015078 IDA hydrogen ion transmembrane transporter activity
GO:0015086 IEA cadmium ion transmembrane transporter activity
GO:0015087 IDA cobalt ion transmembrane transporter activity
GO:0015093 IDA ferrous iron transmembrane transporter activity
GO:0015094 IEA lead ion transmembrane transporter activity
GO:0015099 IEA nickel cation transmembrane transporter activity
GO:0015100 IEA vanadium ion transmembrane transporter activity
GO:0015295 IEA solute:proton symporter activity
GO:0015675 IEA nickel cation transport
GO:0015676 IEA vanadium ion transport
GO:0015684 IDA ferrous iron transport
GO:0015692 IEA lead ion transport
GO:0015992 IDA proton transport
GO:0016021 IEA integral component of membrane
GO:0016151 IEA nickel cation binding
GO:0016324 IEA apical plasma membrane
GO:0022890 IEA inorganic cation transmembrane transporter activity
GO:0030145 IEA manganese ion binding
GO:0031410 IEA cytoplasmic vesicle
GO:0031902 IEA late endosome membrane
GO:0034599 IEA cellular response to oxidative stress
GO:0034755 IDA iron ion transmembrane transport
GO:0035444 IEA nickel cation transmembrane transport
GO:0045177 IEA apical part of cell
GO:0045178 IEA basal part of cell
GO:0046686 IEA response to cadmium ion
GO:0046870 IEA cadmium ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048813 IMP dendrite morphogenesis
GO:0048821 IMP erythrocyte development
GO:0050897 IEA cobalt ion binding
GO:0055037 IDA recycling endosome
GO:0060586 IMP multicellular organismal iron ion homeostasis
GO:0070574 IEA cadmium ion transmembrane transport
GO:0070627 IMP ferrous iron import
GO:0070826 IEA paraferritin complex
GO:0071281 IEA cellular response to iron ion
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071421 IEA manganese ion transmembrane transport
GO:0071456 IEA cellular response to hypoxia
GO:0071577 IEA zinc ion transmembrane transport
GO:0098655 IEA cation transmembrane transport
GO:1902600 IDA hydrogen ion transmembrane transport
GO:1902861 IEA copper ion import into cell

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024295 slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 protein_coding Danio_rerio
ENSG00000110911 SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 protein_coding Homo_sapiens

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