C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000023774 Slc11a2-001 ENSMUSG00000023030 10090 - 15:100387898-100423055 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023774
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023774 12.105±2.63 26.801±5.05 7.673±1.16 7.890±0.55 10.855±3.12 14.789±2.40 7.354±0.42 19.202±0.78 12.401±10.12 11.567±0.31 4.477±1.43 19.461±7.97 6.994±3.05 3.986±1.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007B4 CIL_0007B4_0002 CGP 15:100364542-100425072

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000041 IEA transition metal ion transport
GO:0001666 IEA response to hypoxia
GO:0003032 IEA detection of oxygen
GO:0005375 IEA copper ion transmembrane transporter activity
GO:0005381 IDA iron ion transmembrane transporter activity
GO:0005384 IEA manganese ion transmembrane transporter activity
GO:0005385 IEA zinc ion transmembrane transporter activity
GO:0005506 IEA iron ion binding
GO:0005507 IEA copper ion binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005764 IEA lysosome
GO:0005765 IEA lysosomal membrane
GO:0005768 IDA endosome
GO:0005769 IDA early endosome
GO:0005770 IEA late endosome
GO:0005773 IEA vacuole
GO:0005802 IEA trans-Golgi network
GO:0005886 IDA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0005903 IDA brush border
GO:0006778 IMP porphyrin-containing compound metabolic process
GO:0006779 IMP porphyrin-containing compound biosynthetic process
GO:0006783 IMP heme biosynthetic process
GO:0006824 IDA cobalt ion transport
GO:0006825 IEA copper ion transport
GO:0006826 IDA iron ion transport
GO:0006828 IEA manganese ion transport
GO:0006878 IEA cellular copper ion homeostasis
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007611 IMP learning or memory
GO:0008270 IEA zinc ion binding
GO:0009986 IDA cell surface
GO:0010039 IEA response to iron ion
GO:0010042 IEA response to manganese ion
GO:0010288 IEA response to lead ion
GO:0012505 IDA endomembrane system
GO:0015078 IDA hydrogen ion transmembrane transporter activity
GO:0015086 IEA cadmium ion transmembrane transporter activity
GO:0015087 IDA cobalt ion transmembrane transporter activity
GO:0015093 IDA ferrous iron transmembrane transporter activity
GO:0015094 IEA lead ion transmembrane transporter activity
GO:0015099 IEA nickel cation transmembrane transporter activity
GO:0015100 IEA vanadium ion transmembrane transporter activity
GO:0015295 IEA solute:proton symporter activity
GO:0015675 IEA nickel cation transport
GO:0015676 IEA vanadium ion transport
GO:0015684 IDA ferrous iron transport
GO:0015692 IEA lead ion transport
GO:0015992 IDA proton transport
GO:0016021 IEA integral component of membrane
GO:0016151 IEA nickel cation binding
GO:0016324 IEA apical plasma membrane
GO:0022890 IEA inorganic cation transmembrane transporter activity
GO:0030145 IEA manganese ion binding
GO:0031410 IEA cytoplasmic vesicle
GO:0031902 IEA late endosome membrane
GO:0034599 IEA cellular response to oxidative stress
GO:0035444 IEA nickel cation transmembrane transport
GO:0045177 IEA apical part of cell
GO:0045178 IEA basal part of cell
GO:0046686 IEA response to cadmium ion
GO:0046870 IEA cadmium ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048813 IMP dendrite morphogenesis
GO:0048821 IMP erythrocyte development
GO:0050897 IEA cobalt ion binding
GO:0055037 IDA recycling endosome
GO:0060586 IMP multicellular organismal iron ion homeostasis
GO:0070574 IEA cadmium ion transmembrane transport
GO:0070627 IMP ferrous iron import
GO:0070826 IEA paraferritin complex
GO:0071281 IEA cellular response to iron ion
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071421 IEA manganese ion transmembrane transport
GO:0071456 IEA cellular response to hypoxia
GO:0071577 IEA zinc ion transmembrane transport
GO:0098655 IEA cation transmembrane transport
GO:1902600 IDA hydrogen ion transmembrane transport
GO:1902861 IEA copper ion import into cell

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262051 SLC11A2-006 protein_coding Homo_sapiens 0 2119
ENST00000262052 SLC11A2-002 protein_coding Homo_sapiens 0 1978
ENST00000394904 SLC11A2-201 protein_coding Homo_sapiens 0 1975
ENST00000541174 SLC11A2-005 protein_coding Homo_sapiens 0 1975
ENST00000545993 SLC11A2-008 protein_coding Homo_sapiens 0 1923
ENST00000546488 SLC11A2-012 protein_coding Homo_sapiens 0 346
ENST00000546636 SLC11A2-004 nonsense_mediated_decay Homo_sapiens 0 2113
ENST00000546743 SLC11A2-003 protein_coding Homo_sapiens 0 1882
ENST00000547198 SLC11A2-007 protein_coding Homo_sapiens 0 2134
ENST00000547510 SLC11A2-015 nonsense_mediated_decay Homo_sapiens 0 736
ENST00000547579 SLC11A2-010 protein_coding Homo_sapiens 0 645
ENST00000547688 SLC11A2-001 protein_coding Homo_sapiens 0 1975
ENST00000547732 SLC11A2-014 protein_coding Homo_sapiens 0 569
ENST00000548193 SLC11A2-020 protein_coding Homo_sapiens 0 516
ENST00000549110 SLC11A2-017 protein_coding Homo_sapiens 0 418
ENST00000549193 SLC11A2-016 processed_transcript Homo_sapiens 6e-38 161
ENST00000549625 SLC11A2-018 nonsense_mediated_decay Homo_sapiens 2e-38 163
ENST00000550061 SLC11A2-021 retained_intron Homo_sapiens 0 425
ENST00000550714 SLC11A2-011 protein_coding Homo_sapiens 0 505
ENST00000550782 SLC11A2-009 retained_intron Homo_sapiens 0 787
ENST00000550995 SLC11A2-013 processed_transcript Homo_sapiens 0.00000002 64
ENST00000551215 SLC11A2-024 nonsense_mediated_decay Homo_sapiens 0 472
ENST00000551231 SLC11A2-022 retained_intron Homo_sapiens 0 451

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