C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024242 Map4k3 10090 - 17:80580512-80728093 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025089 Map4k3-201 80580512-80728093 protein_coding
  ENSMUST00000112389 Map4k3-202 80580512-80728093 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025089ENSMUST00000112389
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025089 12.317±3.25 10.411±2.17 15.420±1.84 9.979±2.90 7.344±2.13 9.473±3.57 5.455±1.60 7.574±4.50 3.612±1.41 25.329±3.23 2.067±0.53 9.009±1.64 9.572±3.89 3.303±1.92
ENSMUST00000112389 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.890±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00067B CIL_00067B_0002 CGP 17:80523550-80728093
CIL_0003TC CIL_0003TC_0003 CGP 17:80580512-81001816

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0006468 ISS protein phosphorylation
GO:0009411 ISS response to UV
GO:0034612 IEA response to tumor necrosis factor
GO:0035556 ISS intracellular signal transduction
GO:0050790 IEA regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071357 map4k3b mitogen-activated protein kinase kinase kinase kinase 3b protein_coding Danio_rerio
ENSDARG00000087742 MAP4K3 (2 of 2) mitogen-activated protein kinase kinase kinase kinase 3 protein_coding Danio_rerio
ENSG00000011566 MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 protein_coding Homo_sapiens

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