C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025089 Map4k3-201 ENSMUSG00000024242 10090 - 17:80580512-80728093 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025089
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025089 12.317±3.25 10.411±2.17 15.420±1.84 9.979±2.90 7.344±2.13 9.473±3.57 5.455±1.60 7.574±4.50 3.612±1.41 25.329±3.23 2.067±0.53 9.009±1.64 9.572±3.89 3.303±1.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00067B CIL_00067B_0002 CGP 17:80523550-80728093
CIL_0003TC CIL_0003TC_0003 CGP 17:80580512-81001816

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0006468 ISS protein phosphorylation
GO:0009411 ISS response to UV
GO:0034612 IEA response to tumor necrosis factor
GO:0035556 ISS intracellular signal transduction
GO:0050790 IEA regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000101667 MAP4K3 (2 of 2)-201 protein_coding Danio_rerio 0 702
ENSDART00000155707 MAP4K3 (2 of 2)-001 protein_coding Danio_rerio 0 335
ENST00000263881 MAP4K3-001 protein_coding Homo_sapiens 0 4674
ENST00000341681 MAP4K3-006 protein_coding Homo_sapiens 0 2998
ENST00000414968 MAP4K3-008 nonsense_mediated_decay Homo_sapiens 0 545
ENST00000429397 MAP4K3-005 nonsense_mediated_decay Homo_sapiens 0 643
ENST00000437545 MAP4K3-014 protein_coding Homo_sapiens 0 3007
ENST00000437968 MAP4K3-003 nonsense_mediated_decay Homo_sapiens 0 331
ENST00000475457 MAP4K3-012 retained_intron Homo_sapiens 0 315
ENST00000484274 MAP4K3-002 protein_coding Homo_sapiens 0 486
ENST00000497566 MAP4K3-007 retained_intron Homo_sapiens 0 193

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