C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATP-binding cassette, sub-family G (WHITE), member 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000045714 Abcg8-001 ENSMUSG00000024254 10090 + 17:84683121-84700333 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000045714
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000045714 0.027±0.00 0.084±0.00 0.168±0.00 0.079±0.02 0.721±0.02 0.018±0.00 0.060±0.01 12.430±6.84 0.028±0.01 0.008±0.00 0.056±0.03 0.012±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XP CIL_0001XP_0002 CGP 17:84626496-84683011
CIL_0001XO CIL_0001XO_0002 CGP 17:84658234-84700333
CIL_0001XN CIL_0001XN_0002 CGP 17:84676302-84790789

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0006200 IEA ATP catabolic process
GO:0007584 IEA response to nutrient
GO:0007588 IMP excretion
GO:0010949 IEA negative regulation of intestinal phytosterol absorption
GO:0015248 IEA sterol transporter activity
GO:0015914 IMP phospholipid transport
GO:0015918 IMP sterol transport
GO:0016021 IEA integral component of membrane
GO:0016324 IMP apical plasma membrane
GO:0017127 IMP cholesterol transporter activity
GO:0030299 IC intestinal cholesterol absorption
GO:0033344 IMP cholesterol efflux
GO:0042493 IEA response to drug
GO:0042632 IMP cholesterol homeostasis
GO:0045796 IEA negative regulation of intestinal cholesterol absorption
GO:0046982 IEA protein heterodimerization activity
GO:0055092 IMP sterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000272286 ABCG8-001 protein_coding Homo_sapiens 0 1796

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