C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cadherin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024304 Cdh2 10090 - 18:16588877-16809246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025166 Cdh2-001 16588877-16809246 protein_coding
  ENSMUST00000115850 Cdh2-003 16589023-16670069 protein_coding
  ENSMUST00000152779 Cdh2-002 16771397-16808462 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025166ENSMUST00000115850
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025166 0.965±0.34 9.891±1.52 1.278±0.12 21.209±7.41 1.404±0.34 0.557±0.19 15.100±0.58 0.658±0.18 4.686±1.53 1.082±0.14 0.118±0.07 7.774±3.24 0.581±0.27 1.875±0.19
ENSMUST00000115850 2.542±1.37 10.622±4.83 1.630±0.52 28.198±8.82 1.625±0.65 1.093±0.24 27.695±11.96 1.552±0.56 16.595±7.52 2.090±0.16 0.176±0.10 5.965±2.07 0.745±0.20 6.733±4.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EG CIL_0008EG_0002 VISTA 18:16260468-16863440
CIL_0008EE CIL_0008EE_0002 VISTA 18:16409806-17015755
CIL_0006EO CIL_0006EO_0002 CGP 18:16588877-20002097

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005911 IDA cell-cell junction
GO:0005912 IDA adherens junction
GO:0005913 IEA cell-cell adherens junction
GO:0005916 IDA fascia adherens
GO:0005925 IEA focal adhesion
GO:0007155 IDA cell adhesion
GO:0007156 IDA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 IDA heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0010001 IDA glial cell differentiation
GO:0014704 IDA intercalated disc
GO:0016020 ISO membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0016339 IDA calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016342 IEA catenin complex
GO:0016477 IDA cell migration
GO:0019899 IPI enzyme binding
GO:0019903 IPI protein phosphatase binding
GO:0030027 IDA lamellipodium
GO:0043410 IGI positive regulation of MAPK cascade
GO:0044331 IDA cell-cell adhesion mediated by cadherin
GO:0045202 IDA synapse
GO:0045294 IEA alpha-catenin binding
GO:0045295 IEA gamma-catenin binding
GO:0048514 IMP blood vessel morphogenesis
GO:0051146 IGI striated muscle cell differentiation
GO:0070062 IEA extracellular vesicular exosome
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway
GO:0097150 IDA neuronal stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018693 cdh2 cadherin 2, neuronal protein_coding Danio_rerio
ENSG00000170558 CDH2 cadherin 2, type 1, N-cadherin (neuronal) protein_coding Homo_sapiens

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