C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxysteroid (17-beta) dehydrogenase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024507 Hsd17b4 10090 + 18:50128201-50196269 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025385 Hsd17b4-001 50128201-50196269 protein_coding
  ENSMUST00000127325 Hsd17b4-003 50191324-50195972 retained_intron
  ENSMUST00000139502 Hsd17b4-004 50142369-50146569 retained_intron
  ENSMUST00000152388 Hsd17b4-002 50128494-50142612 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025385ENSMUST00000152388
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025385 33.288±9.75 21.348±2.30 19.744±0.83 15.684±3.77 18.412±3.44 9.709±0.95 16.280±0.75 34.420±5.33 37.542±22.16 23.237±2.48 14.784±1.04 22.002±16.15 45.176±18.55 7.495±1.52
ENSMUST00000152388 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 40.270±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004LE CIL_0004LE_0002 CGP 18:49979427-50196269
CIL_0004B4 CIL_0004B4_0002 CGP 18:50128201-50283019

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000038 IMP very long-chain fatty acid metabolic process
GO:0001649 IEA osteoblast differentiation
GO:0003857 IEA 3-hydroxyacyl-CoA dehydrogenase activity
GO:0005102 IEA receptor binding
GO:0005739 IDA mitochondrion
GO:0005777 IDA peroxisome
GO:0005778 IEA peroxisomal membrane
GO:0006635 IEA fatty acid beta-oxidation
GO:0008209 IEA androgen metabolic process
GO:0008210 IEA estrogen metabolic process
GO:0016020 IEA membrane
GO:0016508 IEA long-chain-enoyl-CoA hydratase activity
GO:0016853 IEA isomerase activity
GO:0033989 IEA 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
GO:0036111 IEA very long-chain fatty-acyl-CoA metabolic process
GO:0036112 IEA medium-chain fatty-acyl-CoA metabolic process
GO:0042803 IEA protein homodimerization activity
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044594 IEA 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0060009 IMP Sertoli cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031873 hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 protein_coding Danio_rerio
ENSG00000133835 HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 protein_coding Homo_sapiens

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