C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: low density lipoprotein receptor class A domain containing 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024544 Ldlrad4 10090 + 18:67933257-68255549 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000063775 Ldlrad4-201 67933257-68255549 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000063775
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000063775 10.356±4.61 7.170±1.02 8.258±0.00 2.960±0.07 6.646±1.15 5.852±2.83 7.042±0.50 9.999±2.69 3.299±1.24 10.390±1.67 1.724±0.68 12.207±2.99 0.504±0.47 1.116±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007Z8 CIL_0007Z8_0002 VISTA 18:67758776-68359713
CIL_0000LB CIL_0000LB_0002 CGP 18:67800107-68255549
CIL_0005Q2 CIL_0005Q2_0003 CGP 18:67933257-68300333

Gene Ontology
GO IDEvidence TypeGO Description
GO:0010719 ISS negative regulation of epithelial to mesenchymal transition
GO:0010991 ISS negative regulation of SMAD protein complex assembly
GO:0016021 IEA integral component of membrane
GO:0030336 ISS negative regulation of cell migration
GO:0030512 IMP negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031901 ISS early endosome membrane
GO:0060394 ISS negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0070412 IEA R-SMAD binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054941 ldlrad4 low density lipoprotein receptor class A domain containing 4 protein_coding Danio_rerio
ENSDARG00000070555 LDLRAD4 (2 of 2) low density lipoprotein receptor class A domain containing 4 protein_coding Danio_rerio
ENSG00000168675 LDLRAD4 low density lipoprotein receptor class A domain containing 4 protein_coding Homo_sapiens

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