C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: helicase, lymphoid specific
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025001 Hells 10090 + 19:38930915-38971051 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025965 Hells-001 38930915-38971051 protein_coding
  ENSMUST00000127968 Hells-005 38943689-38950475 processed_transcript
  ENSMUST00000128949 Hells-002 38934508-38940601 retained_intron
  ENSMUST00000138292 Hells-004 38931030-38940500 retained_intron
  ENSMUST00000145051 Hells-003 38931174-38943914 protein_coding
  ENSMUST00000155465 Hells-006 38931390-38953609 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025965ENSMUST00000127968ENSMUST00000128949ENSMUST00000138292ENSMUST00000145051
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025965 0.817±0.50 0.638±0.25 0.338±0.12 2.226±1.73 0.544±0.30 1.073±0.36 0.044±0.01 0.113±0.04 3.601±4.35 0.324±0.02 0.040±0.03 1.849±0.71 3.479±2.26 2.179±0.35
ENSMUST00000127968 N/A N/A N/A N/A 0.750±0.00 N/A 0.063±0.01 0.128±0.07 N/A 0.224±0.00 0.127±0.06 7.476±0.00 8.510±10.63 6.703±0.00
ENSMUST00000128949 N/A N/A N/A N/A N/A N/A 0.030±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000138292 0.302±0.00 0.319±0.18 N/A N/A N/A 0.291±0.00 0.079±0.01 0.230±0.00 0.069±0.02 N/A N/A 0.592±0.30 N/A N/A
ENSMUST00000145051 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.544±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003RX CIL_0003RX_0002 CGP 19:38836579-38971051
CIL_00067G CIL_00067G_0002 CGP 19:38930915-39042693

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000775 IDA chromosome, centromeric region
GO:0001655 IMP urogenital system development
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005721 IDA pericentric heterochromatin
GO:0006306 IMP DNA methylation
GO:0006342 IMP chromatin silencing
GO:0006346 IMP methylation-dependent chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0007067 IEA mitotic nuclear division
GO:0007275 IMP multicellular organismal development
GO:0010216 IMP maintenance of DNA methylation
GO:0030098 TAS lymphocyte differentiation
GO:0031508 IMP pericentric heterochromatin assembly
GO:0043066 IMP negative regulation of apoptotic process
GO:0046651 IEP lymphocyte proliferation
GO:2001243 IMP negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057738 hells helicase, lymphoid-specific protein_coding Danio_rerio
ENSG00000119969 HELLS helicase, lymphoid-specific protein_coding Homo_sapiens

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