C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000111925 Fgf8-006 ENSMUSG00000025219 10090 - 19:45736990-45742684 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryTestisENSMUST00000111925
Transcript ID Brain Ovary Testis
ENSMUST00000111925 0.168±0.01 0.832±0.29 0.211±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089J CIL_00089J_0002 VISTA 19:45175437-45776961
CIL_000942 CIL_000942_0002 VISTA 19:45193585-45794869
CIL_00099F CIL_00099F_0002 VISTA 19:45434459-46035623
CIL_00099E CIL_00099E_0002 VISTA 19:45446900-46047683
CIL_0005N9 CIL_0005N9_0002 CGP 19:45578254-45742915
CIL_0005NC CIL_0005NC_0002 CGP 19:45736798-45749591

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0001569 IGI patterning of blood vessels
GO:0001658 IMP branching involved in ureteric bud morphogenesis
GO:0001759 IGI organ induction
GO:0001822 IMP kidney development
GO:0001839 IMP neural plate morphogenesis
GO:0001947 IMP heart looping
GO:0001974 IGI blood vessel remodeling
GO:0003007 IMP heart morphogenesis
GO:0003151 IGI outflow tract morphogenesis
GO:0003198 IDA epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0005104 IEA fibroblast growth factor receptor binding
GO:0005576 IEA extracellular region
GO:0006915 IMP apoptotic process
GO:0007368 IMP determination of left/right symmetry
GO:0007507 IMP heart development
GO:0008078 IMP mesodermal cell migration
GO:0008083 IEA growth factor activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0008543 IDA fibroblast growth factor receptor signaling pathway
GO:0009792 IMP embryo development ending in birth or egg hatching
GO:0010628 IMP positive regulation of gene expression
GO:0021537 IMP telencephalon development
GO:0021543 IMP pallium development
GO:0021544 IMP subpallium development
GO:0021798 IMP forebrain dorsal/ventral pattern formation
GO:0021846 IMP cell proliferation in forebrain
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030324 IMP lung development
GO:0030509 IDA BMP signaling pathway
GO:0030539 IDA male genitalia development
GO:0030878 IGI thyroid gland development
GO:0030916 IGI otic vesicle formation
GO:0030917 IMP midbrain-hindbrain boundary development
GO:0035050 IMP embryonic heart tube development
GO:0035108 IGI limb morphogenesis
GO:0035116 IGI embryonic hindlimb morphogenesis
GO:0035909 IGI aorta morphogenesis
GO:0042472 IGI inner ear morphogenesis
GO:0042487 IGI regulation of odontogenesis of dentin-containing tooth
GO:0043066 IGI negative regulation of apoptotic process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045165 IGI cell fate commitment
GO:0045840 IDA positive regulation of mitosis
GO:0046622 IGI positive regulation of organ growth
GO:0048699 IMP generation of neurons
GO:0048853 IMP forebrain morphogenesis
GO:0060037 IGI pharyngeal system development
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060128 IDA corticotropin hormone secreting cell differentiation
GO:0060129 IDA thyroid-stimulating hormone-secreting cell differentiation
GO:0060425 IMP lung morphogenesis
GO:0060445 IGI branching involved in salivary gland morphogenesis
GO:0090134 IMP cell migration involved in mesendoderm migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000123063 fgf18a-201 protein_coding Danio_rerio 0.00000000003 73
ENST00000320185 FGF8-002 protein_coding Homo_sapiens 0 850
ENST00000344255 FGF8-004 protein_coding Homo_sapiens 0 1086
ENST00000346714 FGF8-003 protein_coding Homo_sapiens 0 848
ENST00000347978 FGF8-001 protein_coding Homo_sapiens 0 850
ENST00000469792 FGF8-006 nonsense_mediated_decay Homo_sapiens 0 843
ENST00000485728 FGF8-005 processed_transcript Homo_sapiens 0 850
ENST00000618991 FGF8-201 protein_coding Homo_sapiens 0 848

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