C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025225 Nfkb2 10090 + 19:46304737-46312090 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073116 Nfkb2-201 46304737-46312090 protein_coding
  ENSMUST00000111881 Nfkb2-202 46305695-46312090 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000073116ENSMUST00000111881
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000073116 14.116±2.95 27.444±1.65 10.097±0.71 25.930±14.94 30.603±7.34 5.663±1.82 8.152±0.95 3.346±0.65 20.574±5.24 2.030±0.65 24.309±10.87 5.156±2.16
ENSMUST00000111881 4.605±1.36 5.394±0.89 N/A N/A N/A 2.598±0.33 2.444±0.43 1.044±0.36 4.342±0.00 1.387±0.31 7.583±5.44 2.290±1.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005WJ CIL_0005WJ_0002 CGP 19:46152509-46312090
CIL_0001HR CIL_0001HR_0003 CGP 19:46304737-46327156

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002268 IMP follicular dendritic cell differentiation
GO:0002467 IMP germinal center formation
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0030198 IMP extracellular matrix organization
GO:0033257 IEA Bcl3/NF-kappaB2 complex
GO:0038061 IDA NIK/NF-kappaB signaling
GO:0048511 IEA rhythmic process
GO:0048535 TAS lymph node development
GO:0048536 IMP spleen development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038687 nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 protein_coding Danio_rerio
ENSG00000077150 NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) protein_coding Homo_sapiens

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