C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of fused homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025231 Sufu 10090 + 19:46396896-46488804 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039922 Sufu-001 46396896-46488804 protein_coding
  ENSMUST00000111867 Sufu-002 46396918-46486048 protein_coding
  ENSMUST00000118440 Sufu-004 46397026-46476936 protein_coding
  ENSMUST00000120778 Sufu-003 46397004-46455707 protein_coding
  ENSMUST00000123252 Sufu-006 46457906-46475634 processed_transcript
  ENSMUST00000144341 Sufu-005 46483097-46485982 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039922ENSMUST00000111867ENSMUST00000118440
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039922 5.171±2.57 4.286±1.08 7.128±0.25 5.795±2.01 5.498±2.92 2.556±1.33 1.628±0.63 7.664±2.85 1.540±1.01 6.179±1.35 1.541±0.49 7.307±3.84 3.702±0.74 6.508±2.09
ENSMUST00000111867 N/A N/A N/A N/A N/A 1.796±0.00 N/A N/A 0.442±0.00 N/A N/A 4.648±0.30 N/A 76.721±23.37
ENSMUST00000118440 N/A N/A N/A N/A N/A N/A 0.738±0.00 N/A 0.331±0.03 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MQ CIL_0008MQ_0002 VISTA 19:46318498-46919738
CIL_0005WM CIL_0005WM_0002 CGP 19:46376814-46488804
CIL_00065X CIL_00065X_0002 CGP 19:46396896-46516444

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001843 IMP neural tube closure
GO:0001947 IMP heart looping
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005929 IDA cilium
GO:0007368 IMP determination of left/right symmetry
GO:0008013 IDA beta-catenin binding
GO:0008134 ISO transcription factor binding
GO:0019901 IEA protein kinase binding
GO:0021513 IMP spinal cord dorsal/ventral patterning
GO:0021775 IMP smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 IMP smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0042994 IGI cytoplasmic sequestering of transcription factor
GO:0043588 IMP skin development
GO:0045879 IDA negative regulation of smoothened signaling pathway
GO:0072372 IDA primary cilium
GO:1901621 IMP negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000059 IGI negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000107882 SUFU suppressor of fused homolog (Drosophila) protein_coding Homo_sapiens

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