C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: suppressor of fused homolog (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000111867 Sufu-002 ENSMUSG00000025231 10090 + 19:46396918-46486048 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonLiverOvaryTestisENSMUST00000111867
Transcript ID Colon Liver Ovary Testis
ENSMUST00000111867 1.796±0.00 0.442±0.00 4.648±0.30 76.721±23.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MQ CIL_0008MQ_0002 VISTA 19:46318498-46919738
CIL_0005WM CIL_0005WM_0002 CGP 19:46376814-46488804
CIL_00065X CIL_00065X_0002 CGP 19:46396896-46516444

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001843 IMP neural tube closure
GO:0001947 IMP heart looping
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005929 IDA cilium
GO:0007368 IMP determination of left/right symmetry
GO:0008013 IDA beta-catenin binding
GO:0008134 ISO transcription factor binding
GO:0019901 IEA protein kinase binding
GO:0021513 IMP spinal cord dorsal/ventral patterning
GO:0021775 IMP smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 IMP smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0042994 IGI cytoplasmic sequestering of transcription factor
GO:0043588 IMP skin development
GO:0045879 IDA negative regulation of smoothened signaling pathway
GO:0072372 IDA primary cilium
GO:1901621 IMP negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000059 IGI negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000369899 SUFU-004 protein_coding Homo_sapiens 0 1851
ENST00000369902 SUFU-001 protein_coding Homo_sapiens 0 2148
ENST00000423559 SUFU-006 protein_coding Homo_sapiens 0 1781
ENST00000471000 SUFU-007 processed_transcript Homo_sapiens 0 773

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