C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apurinic/apyrimidinic endonuclease 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025269 Apex2 10090 - X:150519519-150589868 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026303 Apex2-201 150571508-150588149 protein_coding
  ENSMUST00000112719 Apex2-005 150584137-150588081 protein_coding
  ENSMUST00000112720 Apex2-001 150568862-150589844 protein_coding
  ENSMUST00000112721 Apex2-004 150571508-150588096 protein_coding
  ENSMUST00000112725 Apex2-002 150519519-150589844 protein_coding
  ENSMUST00000112727 Apex2-003 150520352-150588082 protein_coding
  ENSMUST00000124521 Apex2-007 150571508-150589868 processed_transcript
  ENSMUST00000138958 Apex2-008 150572459-150586207 processed_transcript
  ENSMUST00000140207 Apex2-009 150572549-150588071 protein_coding
  ENSMUST00000152332 Apex2-006 150571507-150588085 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyOvaryPlacentaENSMUST00000026303ENSMUST00000112720ENSMUST00000112725ENSMUST00000138958ENSMUST00000140207ENSMUST00000152332
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Ovary Placenta
ENSMUST00000026303 6.181±0.88 4.794±1.23 2.253±0.66 5.665±0.00 5.109±1.02 3.282±0.21 6.182±0.78 5.284±1.40 9.630±0.00
ENSMUST00000112720 N/A N/A 0.520±0.09 0.790±0.67 N/A N/A N/A 0.504±0.04 N/A
ENSMUST00000112725 N/A N/A 0.454±0.00 N/A N/A 0.585±0.00 N/A 0.778±0.08 N/A
ENSMUST00000138958 N/A N/A N/A N/A N/A N/A N/A 5.879±1.00 N/A
ENSMUST00000140207 N/A N/A N/A N/A N/A N/A N/A 5.992±0.00 N/A
ENSMUST00000152332 N/A N/A N/A 2.014±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YC CIL_0000YC_0002 CGP X:150519519-150589868

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000737 IBA DNA catabolic process, endonucleolytic
GO:0000738 IBA DNA catabolic process, exonucleolytic
GO:0003677 IEA DNA binding
GO:0003906 IBA DNA-(apurinic or apyrimidinic site) lyase activity
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0006284 IBA base-excision repair
GO:0006310 IEA DNA recombination
GO:0007049 IEA cell cycle
GO:0008270 IEA zinc ion binding
GO:0008311 IBA double-stranded DNA 3'-5' exodeoxyribonuclease activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008472 apex2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 protein_coding Danio_rerio
ENSDARG00000068961 APEX2 (2 of 2) APEX nuclease (apurinic/apyrimidinic endonuclease) 2 protein_coding Danio_rerio
ENSG00000169188 APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 protein_coding Homo_sapiens

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