C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuropilin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025810 Nrp1 10090 + 8:128359073-128505462 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026917 Nrp1-201 128359073-128505462 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026917
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026917 39.342±5.93 27.825±2.52 11.134±0.00 10.419±6.11 29.091±0.81 6.422±0.99 27.474±2.23 25.177±1.15 6.961±4.75 83.375±7.34 4.082±0.67 17.031±5.64 4.487±2.83 0.691±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000CM CIL_0000CM_0002 CGP 8:127063893-128505462
CIL_0000CP CIL_0000CP_0002 CGP 8:128359073-128733200

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0001569 IMP patterning of blood vessels
GO:0001764 IMP neuron migration
GO:0002040 IMP sprouting angiogenesis
GO:0002042 IMP cell migration involved in sprouting angiogenesis
GO:0005021 IMP vascular endothelial growth factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005769 IDA early endosome
GO:0005829 IEA cytosol
GO:0005883 IDA neurofilament
GO:0005886 IDA plasma membrane
GO:0005925 IEA focal adhesion
GO:0007155 IEA cell adhesion
GO:0007411 IMP axon guidance
GO:0007413 IMP axonal fasciculation
GO:0007507 IGI heart development
GO:0008045 IMP motor neuron axon guidance
GO:0008201 IEA heparin binding
GO:0009611 IEA response to wounding
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0016358 IMP dendrite development
GO:0016477 IMP cell migration
GO:0017154 IGI semaphorin receptor activity
GO:0019838 IPI growth factor binding
GO:0021612 IMP facial nerve structural organization
GO:0021636 IMP trigeminal nerve morphogenesis
GO:0021637 IMP trigeminal nerve structural organization
GO:0021649 IMP vestibulocochlear nerve structural organization
GO:0021675 IMP nerve development
GO:0021785 IMP branchiomotor neuron axon guidance
GO:0021828 IMP gonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO:0030424 IDA axon
GO:0030426 IEA growth cone
GO:0030517 IGI negative regulation of axon extension
GO:0031290 IMP retinal ganglion cell axon guidance
GO:0035729 IEA cellular response to hepatocyte growth factor stimulus
GO:0035767 IEA endothelial cell chemotaxis
GO:0035924 IMP cellular response to vascular endothelial growth factor stimulus
GO:0036486 IMP ventral trunk neural crest cell migration
GO:0038085 IPI vascular endothelial growth factor binding
GO:0038190 IMP VEGF-activated neuropilin signaling pathway
GO:0043025 IEA neuronal cell body
GO:0043049 IMP otic placode formation
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0046872 IEA metal ion binding
GO:0048008 IEA platelet-derived growth factor receptor signaling pathway
GO:0048010 IMP vascular endothelial growth factor receptor signaling pathway
GO:0048012 IEA hepatocyte growth factor receptor signaling pathway
GO:0048485 IMP sympathetic nervous system development
GO:0048666 IMP neuron development
GO:0048841 IDA regulation of axon extension involved in axon guidance
GO:0048842 IMP positive regulation of axon extension involved in axon guidance
GO:0048843 IDA negative regulation of axon extension involved in axon guidance
GO:0048844 IMP artery morphogenesis
GO:0048846 IMP axon extension involved in axon guidance
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918 IMP positive chemotaxis
GO:0060385 IMP axonogenesis involved in innervation
GO:0060666 IGI dichotomous subdivision of terminal units involved in salivary gland branching
GO:0060978 IMP angiogenesis involved in coronary vascular morphogenesis
GO:0060980 IC cell migration involved in coronary vasculogenesis
GO:0060982 IMP coronary artery morphogenesis
GO:0061299 IMP retina vasculature morphogenesis in camera-type eye
GO:0061441 IMP renal artery morphogenesis
GO:0061549 IMP sympathetic ganglion development
GO:0061551 IMP trigeminal ganglion development
GO:0061552 IMP ganglion morphogenesis
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071526 IGI semaphorin-plexin signaling pathway
GO:0071679 IMP commissural neuron axon guidance
GO:0090259 IMP regulation of retinal ganglion cell axon guidance
GO:0097374 IMP sensory neuron axon guidance
GO:0097443 IDA sorting endosome
GO:0097490 IMP sympathetic neuron projection extension
GO:0097491 IMP sympathetic neuron projection guidance
GO:1901166 IMP neural crest cell migration involved in autonomic nervous system development
GO:1901998 IMP toxin transport
GO:1902285 IMP semaphorin-plexin signaling pathway involved in neuron projection guidance
GO:1902287 IMP semaphorin-plexin signaling pathway involved in axon guidance
GO:1902336 IMP positive regulation of retinal ganglion cell axon guidance
GO:1902378 IMP VEGF-activated neuropilin signaling pathway involved in axon guidance
GO:1902946 IMP protein localization to early endosome
GO:1903375 IMP facioacoustic ganglion development
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027290 nrp1b neuropilin 1b protein_coding Danio_rerio
ENSDARG00000071865 nrp1a neuropilin 1a protein_coding Danio_rerio
ENSG00000099250 NRP1 neuropilin 1 protein_coding Homo_sapiens

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