C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eyes absent 1 homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025932 Eya1 10090 - 1:14168954-14310235 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027066 Eya1-201 14168954-14310200 protein_coding
  ENSMUST00000080664 Eya1-002 14169666-14310119 protein_coding
  ENSMUST00000168081 Eya1-001 14168958-14310235 protein_coding
  ENSMUST00000185329 Eya1-003 14301204-14310051 retained_intron
  ENSMUST00000185453 Eya1-006 14270707-14304628 protein_coding
  ENSMUST00000187790 Eya1-005 14270775-14309836 protein_coding
  ENSMUST00000188857 Eya1-007 14252600-14304619 protein_coding
  ENSMUST00000189526 Eya1-008 14207926-14231492 protein_coding
  ENSMUST00000190337 Eya1-004 14170643-14304570 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027066ENSMUST00000080664ENSMUST00000168081ENSMUST00000185329ENSMUST00000185453ENSMUST00000187790ENSMUST00000188857ENSMUST00000189526ENSMUST00000190337
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027066 0.106±0.00 0.294±0.00 0.375±0.09 0.196±0.06 0.217±0.02 0.235±0.15 N/A 0.078±0.02 0.008±0.01 0.293±0.07 N/A 0.202±0.09 0.015±0.00 N/A
ENSMUST00000080664 0.176±0.07 0.279±0.08 N/A 0.316±0.04 0.144±0.09 0.070±0.02 0.124±0.00 0.038±0.00 0.010±0.00 N/A N/A 0.139±0.06 0.017±0.00 0.144±0.00
ENSMUST00000168081 0.103±0.03 0.708±0.19 0.150±0.00 N/A 0.071±0.00 0.201±0.00 0.139±0.06 N/A 0.003±0.00 N/A 1.057±0.00 0.238±0.09 0.033±0.00 0.118±0.00
ENSMUST00000185329 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.188±0.00 N/A N/A
ENSMUST00000185453 N/A N/A N/A N/A N/A 0.115±0.03 N/A 0.267±0.11 0.024±0.00 N/A N/A N/A N/A N/A
ENSMUST00000187790 0.550±0.00 N/A N/A N/A N/A N/A N/A N/A 0.017±0.00 N/A N/A N/A N/A N/A
ENSMUST00000188857 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.793±0.00 N/A N/A
ENSMUST00000189526 N/A N/A N/A N/A N/A N/A N/A N/A 0.045±0.00 N/A N/A N/A 0.629±0.00 N/A
ENSMUST00000190337 0.317±0.05 0.626±0.15 N/A 0.581±0.25 0.499±0.18 0.176±0.08 0.167±0.05 0.127±0.06 0.004±0.00 0.563±0.12 2.088±0.00 0.559±0.38 0.099±0.02 0.344±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00012M CIL_00012M_0002 CGP 1:13668771-14310235
CIL_0007NF CIL_0007NF_0002 UCNEbase 1:13861373-14636027
CIL_0003F4 CIL_0003F4_0002 CGP 1:14168954-14755992

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000132 IGI establishment of mitotic spindle orientation
GO:0001656 IMP metanephros development
GO:0001657 IGI ureteric bud development
GO:0001658 IGI branching involved in ureteric bud morphogenesis
GO:0003151 IMP outflow tract morphogenesis
GO:0003723 IDA RNA binding
GO:0004725 IDA protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0006302 ISS double-strand break repair
GO:0006351 IEA transcription, DNA-templated
GO:0006470 IDA protein dephosphorylation
GO:0007389 IGI pattern specification process
GO:0007501 IDA mesodermal cell fate specification
GO:0009887 IMP organ morphogenesis
GO:0010212 ISS response to ionizing radiation
GO:0014706 IGI striated muscle tissue development
GO:0016576 ISS histone dephosphorylation
GO:0016925 IDA protein sumoylation
GO:0032993 IDA protein-DNA complex
GO:0034613 IMP cellular protein localization
GO:0035088 IMP establishment or maintenance of apical/basal cell polarity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0035909 IMP aorta morphogenesis
GO:0042472 IMP inner ear morphogenesis
GO:0042473 IMP outer ear morphogenesis
GO:0042474 IMP middle ear morphogenesis
GO:0043234 IDA protein complex
GO:0045165 IMP cell fate commitment
GO:0045664 IMP regulation of neuron differentiation
GO:0045739 ISS positive regulation of DNA repair
GO:0045747 IMP positive regulation of Notch signaling pathway
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048665 IGI neuron fate specification
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0048752 IMP semicircular canal morphogenesis
GO:0048856 IGI anatomical structure development
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0060037 IMP pharyngeal system development
GO:0060487 IGI lung epithelial cell differentiation
GO:0071599 IGI otic vesicle development
GO:0071600 IMP otic vesicle morphogenesis
GO:0072513 IGI positive regulation of secondary heart field cardioblast proliferation
GO:0090103 IMP cochlea morphogenesis
GO:2001240 IMP negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014259 eya1 eyes absent homolog 1 protein_coding Danio_rerio
ENSG00000104313 EYA1 EYA transcriptional coactivator and phosphatase 1 protein_coding Homo_sapiens

Loading