C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eyes absent 1 homolog (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000027066 Eya1-201 ENSMUSG00000025932 10090 - 1:14168954-14310200 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaENSMUST00000027066
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta
ENSMUST00000027066 0.106±0.00 0.294±0.00 0.375±0.09 0.196±0.06 0.217±0.02 0.235±0.15 0.078±0.02 0.008±0.01 0.293±0.07 0.202±0.09 0.015±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00012M CIL_00012M_0002 CGP 1:13668771-14310235
CIL_0007NF CIL_0007NF_0002 UCNEbase 1:13861373-14636027
CIL_0003F4 CIL_0003F4_0002 CGP 1:14168954-14755992

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000132 IGI establishment of mitotic spindle orientation
GO:0001656 IMP metanephros development
GO:0001657 IGI ureteric bud development
GO:0001658 IGI branching involved in ureteric bud morphogenesis
GO:0003151 IMP outflow tract morphogenesis
GO:0003723 IDA RNA binding
GO:0004725 IDA protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0006302 ISS double-strand break repair
GO:0006351 IEA transcription, DNA-templated
GO:0006470 IDA protein dephosphorylation
GO:0007389 IGI pattern specification process
GO:0007501 IDA mesodermal cell fate specification
GO:0009887 IMP organ morphogenesis
GO:0010212 ISS response to ionizing radiation
GO:0014706 IGI striated muscle tissue development
GO:0016576 ISS histone dephosphorylation
GO:0016925 IDA protein sumoylation
GO:0032993 IDA protein-DNA complex
GO:0034613 IMP cellular protein localization
GO:0035088 IMP establishment or maintenance of apical/basal cell polarity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0035909 IMP aorta morphogenesis
GO:0042472 IMP inner ear morphogenesis
GO:0042473 IMP outer ear morphogenesis
GO:0042474 IMP middle ear morphogenesis
GO:0043234 IDA protein complex
GO:0045165 IMP cell fate commitment
GO:0045664 IMP regulation of neuron differentiation
GO:0045739 ISS positive regulation of DNA repair
GO:0045747 IMP positive regulation of Notch signaling pathway
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048665 IGI neuron fate specification
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0048752 IMP semicircular canal morphogenesis
GO:0048856 IGI anatomical structure development
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0060037 IMP pharyngeal system development
GO:0060487 IGI lung epithelial cell differentiation
GO:0071599 IGI otic vesicle development
GO:0071600 IMP otic vesicle morphogenesis
GO:0072513 IGI positive regulation of secondary heart field cardioblast proliferation
GO:0090103 IMP cochlea morphogenesis
GO:2001240 IMP negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000134221 eya1-002 protein_coding Danio_rerio 0 1083
ENSDART00000012253 eya1-201 protein_coding Danio_rerio 0 1003
ENSDART00000081595 eya1-202 protein_coding Danio_rerio 0 915
ENSDART00000136443 eya1-001 protein_coding Danio_rerio 0 915
ENSDART00000138119 eya1-003 processed_transcript Danio_rerio 0 254
ENSDART00000142058 eya1-004 protein_coding Danio_rerio 0 211
ENST00000303824 EYA1-010 protein_coding Homo_sapiens 0 2926
ENST00000340726 EYA1-001 protein_coding Homo_sapiens 0 3265
ENST00000355286 EYA4-008 protein_coding Homo_sapiens 0 470
ENST00000367895 EYA4-001 protein_coding Homo_sapiens 0 470
ENST00000388740 EYA1-201 protein_coding Homo_sapiens 0 2636
ENST00000388741 EYA1-012 protein_coding Homo_sapiens 0 2649
ENST00000388742 EYA1-002 protein_coding Homo_sapiens 0 2894
ENST00000388743 EYA1-011 protein_coding Homo_sapiens 0 2567
ENST00000419131 EYA1-005 protein_coding Homo_sapiens 0 1343
ENST00000422295 EYA1-007 retained_intron Homo_sapiens 0 324
ENST00000465115 EYA1-003 nonsense_mediated_decay Homo_sapiens 0 2268
ENST00000493349 EYA1-008 nonsense_mediated_decay Homo_sapiens 0 436
ENST00000496494 EYA1-004 retained_intron Homo_sapiens 0 2015
ENST00000531901 EYA4-009 protein_coding Homo_sapiens 0 470

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