C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuropilin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025969 Nrp2 10090 + 1:62703285-62818695 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027112 Nrp2-005 62703702-62796981 protein_coding
  ENSMUST00000063594 Nrp2-002 62703702-62818695 protein_coding
  ENSMUST00000075144 Nrp2-006 62703285-62818695 protein_coding
  ENSMUST00000102822 Nrp2-001 62703285-62818695 protein_coding
  ENSMUST00000114155 Nrp2-004 62703702-62799314 protein_coding
  ENSMUST00000114157 Nrp2-003 62703702-62818695 protein_coding
  ENSMUST00000126344 Nrp2-007 62703285-62739932 retained_intron

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027112ENSMUST00000063594ENSMUST00000075144ENSMUST00000102822ENSMUST00000114155ENSMUST00000114157ENSMUST00000126344
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027112 3.987±0.06 N/A N/A N/A 2.010±0.20 6.448±0.97 1.573±0.00 1.514±0.30 0.410±0.00 3.174±0.49 N/A N/A 0.771±0.00 0.392±0.13
ENSMUST00000063594 3.034±0.78 N/A 18.662±0.06 9.064±4.76 4.212±2.00 N/A 2.448±0.87 2.221±0.37 1.125±0.61 3.192±1.05 0.825±0.30 7.211±3.78 2.240±0.83 0.348±0.17
ENSMUST00000075144 2.234±0.00 6.660±2.00 N/A N/A 6.972±0.57 8.218±3.48 1.283±0.00 3.013±1.95 0.925±0.57 2.978±0.21 0.367±0.00 7.514±2.82 0.887±0.00 N/A
ENSMUST00000102822 5.276±2.09 8.199±2.13 14.593±0.34 7.955±4.94 4.192±0.79 7.197±2.08 2.987±0.33 2.727±0.38 0.634±0.41 4.603±1.69 0.389±0.16 6.418±1.56 1.764±0.80 0.132±0.06
ENSMUST00000114155 2.508±0.53 3.137±0.59 32.307±4.16 3.496±1.42 2.860±1.00 8.758±0.95 1.543±0.14 1.858±0.30 0.208±0.10 4.073±0.42 0.453±0.04 5.182±1.00 0.992±0.58 0.289±0.06
ENSMUST00000114157 N/A N/A N/A N/A 1.589±0.00 N/A N/A N/A 0.596±0.30 N/A 0.194±0.00 N/A 1.053±0.00 0.141±0.00
ENSMUST00000126344 N/A 4.019±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001R1 CIL_0001R1_0002 CGP 1:61638824-62818695
CIL_00039J CIL_00039J_0002 CGP 1:62703285-63114667

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001755 IMP neural crest cell migration
GO:0001764 IMP neuron migration
GO:0005021 IEA vascular endothelial growth factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005886 IC plasma membrane
GO:0007155 IEA cell adhesion
GO:0007411 IMP axon guidance
GO:0007507 IGI heart development
GO:0008201 IEA heparin binding
GO:0016021 IEA integral component of membrane
GO:0017154 IDA semaphorin receptor activity
GO:0021612 IMP facial nerve structural organization
GO:0021649 IMP vestibulocochlear nerve structural organization
GO:0021675 IMP nerve development
GO:0021828 IMP gonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO:0030424 IDA axon
GO:0036486 IMP ventral trunk neural crest cell migration
GO:0038084 IEA vascular endothelial growth factor signaling pathway
GO:0046872 IEA metal ion binding
GO:0048846 IMP axon extension involved in axon guidance
GO:0050919 IMP negative chemotaxis
GO:0061549 IMP sympathetic ganglion development
GO:0061551 IMP trigeminal ganglion development
GO:0061552 IMP ganglion morphogenesis
GO:0097374 IMP sensory neuron axon guidance
GO:0097490 IMP sympathetic neuron projection extension
GO:0097491 IMP sympathetic neuron projection guidance
GO:1901166 IMP neural crest cell migration involved in autonomic nervous system development
GO:1902285 IMP semaphorin-plexin signaling pathway involved in neuron projection guidance
GO:1903375 IMP facioacoustic ganglion development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038446 nrp2b neuropilin 2b protein_coding Danio_rerio
ENSDARG00000096546 nrp2a neuropilin 2a protein_coding Danio_rerio
ENSG00000118257 NRP2 neuropilin 2 protein_coding Homo_sapiens

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