C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuropilin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118257 NRP2 9606 + 2:205681990-205798133 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272849 NRP2-002 205683291-205779714 protein_coding
  ENST00000357118 NRP2-003 205683260-205777156 protein_coding
  ENST00000357785 NRP2-005 205683260-205795172 protein_coding
  ENST00000360409 NRP2-001 205682500-205798133 protein_coding
  ENST00000412873 NRP2-004 205683291-205795058 protein_coding
  ENST00000417189 NRP2-006 205682507-205743698 protein_coding
  ENST00000450507 NRP2-009 205682501-205716246 protein_coding
  ENST00000460987 NRP2-016 205749691-205763807 retained_intron
  ENST00000464003 NRP2-007 205681990-205701557 processed_transcript
  ENST00000467850 NRP2-015 205764337-205795121 processed_transcript
  ENST00000468256 NRP2-017 205752468-205763806 retained_intron
  ENST00000472299 NRP2-014 205763801-205767064 retained_intron
  ENST00000477199 NRP2-011 205722265-205723922 retained_intron
  ENST00000478013 NRP2-008 205682658-205697909 retained_intron
  ENST00000478054 NRP2-012 205739936-205743693 processed_transcript
  ENST00000483917 NRP2-010 205685793-205697734 retained_intron
  ENST00000485684 NRP2-013 205763735-205768481 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000272849ENST00000357118ENST00000357785ENST00000360409ENST00000412873ENST00000450507ENST00000467850ENST00000478013ENST00000485684
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000272849 N/A 1.972±0.00 0.142±0.00 1.212±0.00 2.483±0.41 4.967±3.27 0.291±0.00 N/A 3.598±3.11 N/A 0.177±0.00 5.254±2.87 3.808±0.59 1.718±0.00
ENST00000357118 N/A N/A 0.246±0.00 0.459±0.00 2.462±0.00 2.001±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000357785 N/A N/A N/A N/A N/A N/A N/A 0.806±0.00 1.091±0.00 3.230±0.00 0.219±0.00 N/A N/A N/A
ENST00000360409 3.744±0.00 1.075±0.00 N/A 1.054±0.00 1.776±0.00 1.754±0.00 0.446±0.00 N/A 1.575±1.27 1.056±0.00 N/A 5.853±4.50 8.857±5.68 1.274±0.00
ENST00000412873 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.449±0.00 N/A N/A N/A
ENST00000450507 N/A N/A 1.076±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000467850 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.295±0.00 N/A N/A N/A
ENST00000478013 N/A N/A 0.535±0.00 N/A N/A N/A N/A N/A 18.493±0.00 N/A N/A 13.111±0.00 N/A N/A
ENST00000485684 N/A N/A 0.374±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001R1 CIL_0001R1_0001 CGP 2:204545793-205798133
CIL_00039J CIL_00039J_0001 CGP 2:205681990-206086303

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 NAS:IEA angiogenesis
GO:0001755 IEA neural crest cell migration
GO:0001764 IEA neuron migration
GO:0001938 TAS positive regulation of endothelial cell proliferation
GO:0002116 NAS semaphorin receptor complex
GO:0004872 TAS receptor activity
GO:0005021 NAS:IEA vascular endothelial growth factor-activated receptor activity
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0007155 NAS cell adhesion
GO:0007411 NAS:IEA axon guidance
GO:0007507 IEA heart development
GO:0008201 IEA heparin binding
GO:0010595 TAS positive regulation of endothelial cell migration
GO:0016020 TAS:IEA membrane
GO:0016021 NAS integral component of membrane
GO:0017154 NAS:IEA semaphorin receptor activity
GO:0019838 TAS growth factor binding
GO:0019955 NAS cytokine binding
GO:0021612 IEA facial nerve structural organization
GO:0021649 IEA vestibulocochlear nerve structural organization
GO:0021675 ISS nerve development
GO:0021828 IEA gonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO:0030424 IEA axon
GO:0036486 IEA ventral trunk neural crest cell migration
GO:0038084 IEA vascular endothelial growth factor signaling pathway
GO:0046872 IEA metal ion binding
GO:0048010 TAS vascular endothelial growth factor receptor signaling pathway
GO:0048846 ISS axon extension involved in axon guidance
GO:0050919 IEA negative chemotaxis
GO:0061549 ISS sympathetic ganglion development
GO:0061551 IEA trigeminal ganglion development
GO:0061552 IEA ganglion morphogenesis
GO:0097374 IEA sensory neuron axon guidance
GO:0097490 ISS sympathetic neuron projection extension
GO:0097491 ISS sympathetic neuron projection guidance
GO:1901166 IEA neural crest cell migration involved in autonomic nervous system development
GO:1902285 ISS semaphorin-plexin signaling pathway involved in neuron projection guidance
GO:1903375 IEA facioacoustic ganglion development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038446 nrp2b neuropilin 2b protein_coding Danio_rerio
ENSDARG00000096546 nrp2a neuropilin 2a protein_coding Danio_rerio
ENSMUSG00000025969 Nrp2 neuropilin 2 protein_coding Mus_musculus

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