C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 1 (chaperonin)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025980 Hspd1 10090 - 1:55077835-55088243 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027123 Hspd1-001 55077835-55088024 protein_coding
  ENSMUST00000127861 Hspd1-002 55083067-55088243 protein_coding
  ENSMUST00000144077 Hspd1-003 55084533-55088243 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027123ENSMUST00000127861
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027123 25.715±0.76 42.630±5.63 33.874±0.04 39.190±0.59 17.316±3.25 9.999±0.81 33.091±3.36 51.256±10.43 97.063±62.31 7.633±1.30 50.137±4.84 38.428±59.84 91.750±55.16 4.220±1.38
ENSMUST00000127861 N/A N/A N/A 43.447±0.00 N/A 4.694±0.00 N/A N/A N/A 5.084±0.77 N/A N/A 456.749±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007X7 CIL_0007X7_0002 VISTA 1:54604981-55208576
CIL_0002KH CIL_0002KH_0002 CGP 1:55052770-55088243
CIL_00042Q CIL_00042Q_0003 CGP 1:55077835-55091307

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001530 IDA lipopolysaccharide binding
GO:0002039 IEA p53 binding
GO:0002368 IEA B cell cytokine production
GO:0002755 IEA MyD88-dependent toll-like receptor signaling pathway
GO:0002842 IEA positive regulation of T cell mediated immune response to tumor cell
GO:0003725 ISO double-stranded RNA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005769 IEA early endosome
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005905 IEA coated pit
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006986 IEA response to unfolded protein
GO:0009986 IEA cell surface
GO:0016020 IEA membrane
GO:0019907 IEA cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0030135 IEA coated vesicle
GO:0030141 IDA secretory granule
GO:0032727 IDA positive regulation of interferon-alpha production
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0032733 IEA positive regulation of interleukin-10 production
GO:0032735 IEA positive regulation of interleukin-12 production
GO:0032755 IEA positive regulation of interleukin-6 production
GO:0042100 IEA B cell proliferation
GO:0042110 IDA T cell activation
GO:0042113 IEA B cell activation
GO:0043032 IEA positive regulation of macrophage activation
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043234 ISS protein complex
GO:0044822 IEA poly(A) RNA binding
GO:0046696 IEA lipopolysaccharide receptor complex
GO:0048291 IEA isotype switching to IgG isotypes
GO:0050870 IDA positive regulation of T cell activation
GO:0051087 IEA chaperone binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056160 hspd1 heat shock 60kD protein 1 (chaperonin) protein_coding Danio_rerio
ENSG00000144381 HSPD1 heat shock 60kDa protein 1 (chaperonin) protein_coding Homo_sapiens

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