C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium response factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026017 Carf 10090 + 1:60098247-60153953 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027171 Carf-007 60108102-60150800 protein_coding
  ENSMUST00000124986 Carf-003 60098264-60125977 protein_coding
  ENSMUST00000130075 Carf-002 60098247-60151032 nonsense_mediated_decay
  ENSMUST00000132949 Carf-005 60141448-60148027 nonsense_mediated_decay
  ENSMUST00000150008 Carf-004 60098264-60109061 retained_intron
  ENSMUST00000180952 Carf-201 60108081-60150729 protein_coding
  ENSMUST00000186107 Carf-008 60108102-60150800 nonsense_mediated_decay
  ENSMUST00000186779 Carf-009 60139796-60142211 retained_intron
  ENSMUST00000187978 Carf-001 60105344-60153953 protein_coding
  ENSMUST00000191232 Carf-006 60101246-60104480 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027171ENSMUST00000130075ENSMUST00000180952ENSMUST00000187978
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027171 1.659±0.00 N/A N/A N/A N/A 0.855±0.00 0.504±0.00 0.703±0.00 N/A 1.110±0.00 N/A 0.915±0.00 N/A N/A
ENSMUST00000130075 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.565±0.00 N/A N/A
ENSMUST00000180952 2.420±0.00 N/A N/A N/A 1.650±0.55 N/A N/A N/A N/A N/A N/A 1.435±0.08 N/A 7.762±0.88
ENSMUST00000187978 1.080±0.24 1.286±0.24 0.822±0.00 1.774±0.63 1.044±0.17 0.598±0.14 0.412±0.03 0.639±0.12 0.804±0.24 0.939±0.19 0.635±0.07 1.286±0.43 1.021±0.17 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00020R CIL_00020R_0002 CGP 1:59982490-60098645
CIL_00020W CIL_00020W_0002 CGP 1:60069785-60153953
CIL_00020V CIL_00020V_0002 CGP 1:60098247-60338328

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 ISS DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0035865 ISS cellular response to potassium ion
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0061400 ISS positive regulation of transcription from RNA polymerase II promoter in response to calcium ion
GO:0071277 ISS cellular response to calcium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019950 carf calcium responsive transcription factor protein_coding Danio_rerio
ENSG00000138380 CARF calcium responsive transcription factor protein_coding Homo_sapiens

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