C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox transcription factor 1 alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026686 Lmx1a 10090 + 1:167689237-167848741 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028003 Lmx1a-001 167689557-167848741 protein_coding
  ENSMUST00000111377 Lmx1a-002 167689237-167848741 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028003ENSMUST00000111377
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028003 0.050±0.01 0.040±0.00 0.026±0.00 2.848±1.31 0.206±0.05 0.863±0.20 N/A N/A N/A N/A N/A 0.101±0.06 N/A N/A
ENSMUST00000111377 0.044±0.01 N/A 0.016±0.00 0.082±0.00 0.087±0.04 N/A 0.018±0.00 0.027±0.01 0.048±0.03 0.013±0.00 0.048±0.02 0.064±0.03 1.216±1.26 0.034±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005MM CIL_0005MM_0002 CGP 1:167598384-167848741

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IMP regulation of cell growth
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007411 IMP axon guidance
GO:0007417 IMP central nervous system development
GO:0007420 IEA brain development
GO:0008270 IEA zinc ion binding
GO:0010468 IMP regulation of gene expression
GO:0021542 IMP dentate gyrus development
GO:0021549 IMP cerebellum development
GO:0021766 IMP hippocampus development
GO:0021953 IMP central nervous system neuron differentiation
GO:0030182 IMP neuron differentiation
GO:0030901 IMP midbrain development
GO:0043565 IEA sequence-specific DNA binding
GO:0045665 IMP negative regulation of neuron differentiation
GO:0071542 IMP dopaminergic neuron differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020354 lmx1a LIM homeobox transcription factor 1, alpha protein_coding Danio_rerio
ENSG00000162761 LMX1A LIM homeobox transcription factor 1, alpha protein_coding Homo_sapiens

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