C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NIMA (never in mitosis gene a)-related expressed kinase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026749 Nek6 10090 + 2:38511643-38588041 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054234 Nek6-001 38511643-38588041 protein_coding
  ENSMUST00000112895 Nek6-003 38511814-38585766 protein_coding
  ENSMUST00000112902 Nek6-002 38511668-38587480 protein_coding
  ENSMUST00000151683 Nek6-004 38514581-38557849 protein_coding
  ENSMUST00000156726 Nek6-005 38514626-38560910 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungOvaryPlacentaENSMUST00000054234ENSMUST00000112895ENSMUST00000112902ENSMUST00000151683
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Ovary Placenta
ENSMUST00000054234 11.367±2.87 15.826±2.49 9.974±1.25 12.428±6.16 36.551±3.89 4.805±1.70 16.747±4.69 11.341±3.96 41.285±15.65 18.794±1.99
ENSMUST00000112895 17.577±6.25 N/A 10.245±0.00 16.159±4.43 N/A 5.075±0.00 8.961±0.00 6.100±0.65 10.613±3.53 37.990±17.13
ENSMUST00000112902 N/A 6.134±0.68 N/A N/A N/A N/A 10.254±1.28 N/A 5.872±0.00 17.524±9.36
ENSMUST00000151683 N/A 63.572±6.04 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MV CIL_0007MV_0002 UCNEbase 2:38111928-38614796
CIL_0008N3 CIL_0008N3_0002 VISTA 2:38235055-38837083
CIL_00098L CIL_00098L_0002 VISTA 2:38294702-38895720
CIL_0006WH CIL_0006WH_0002 CGP 2:38339281-38588041
CIL_0006WG CIL_0006WG_0002 CGP 2:38511643-38644087

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IEA protein binding
GO:0005524 IEA:ISS ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006468 ISS protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007059 ISS chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0007165 IEA signal transduction
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019894 IEA kinesin binding
GO:0019901 ISS protein kinase binding
GO:0030071 ISS regulation of mitotic metaphase/anaphase transition
GO:0031572 ISS G2 DNA damage checkpoint
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046777 ISS protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037963 nek6 NIMA (never in mitosis gene a)-related kinase 6 protein_coding Danio_rerio
ENSG00000119408 NEK6 NIMA-related kinase 6 protein_coding Homo_sapiens

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