C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: paired box 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028355 Pax8-001 ENSMUSG00000026976 10090 - 2:24420560-24475599 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverOvaryPlacentaTestisENSMUST00000028355
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENSMUST00000028355 4.739±3.33 0.014±0.00 0.629±0.71 0.029±0.00 0.229±0.00 23.219±2.04 0.019±0.01 6.634±2.45 2.940±3.64 0.475±0.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000196 CIL_000196_0002 CGP 2:24367580-24475599

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 ISS RNA polymerase II core promoter sequence-specific DNA binding
GO:0001655 IGI urogenital system development
GO:0001656 IGI metanephros development
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001822 IEA kidney development
GO:0001823 IMP mesonephros development
GO:0003337 IEA mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003677 ISS DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 ISS nucleoplasm
GO:0005667 TAS transcription factor complex
GO:0006351 IDA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0007417 IEP central nervous system development
GO:0009887 TAS organ morphogenesis
GO:0030154 IMP cell differentiation
GO:0030878 IGI thyroid gland development
GO:0039003 IEP pronephric field specification
GO:0042472 IGI inner ear morphogenesis
GO:0042981 IMP regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 ISO positive regulation of transcription from RNA polymerase II promoter
GO:0048793 IMP pronephros development
GO:0071371 IEA cellular response to gonadotropin stimulus
GO:0071599 IEA otic vesicle development
GO:0072050 IEP S-shaped body morphogenesis
GO:0072073 IEP kidney epithelium development
GO:0072108 IMP positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0072164 IEP mesonephric tubule development
GO:0072207 IEA metanephric epithelium development
GO:0072221 IMP metanephric distal convoluted tubule development
GO:0072278 IEA metanephric comma-shaped body morphogenesis
GO:0072284 IEA metanephric S-shaped body morphogenesis
GO:0072289 IMP metanephric nephron tubule formation
GO:0072305 IMP negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
GO:0072307 IMP regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090190 IMP positive regulation of branching involved in ureteric bud morphogenesis
GO:1900212 IMP negative regulation of mesenchymal cell apoptotic process involved in metanephros development
GO:1900215 IMP negative regulation of apoptotic process involved in metanephric collecting duct development
GO:1900218 IMP negative regulation of apoptotic process involved in metanephric nephron tubule development
GO:2000594 IMP positive regulation of metanephric DCT cell differentiation
GO:2000611 IMP positive regulation of thyroid hormone generation
GO:2000612 ISS regulation of thyroid-stimulating hormone secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000029014 pax8-201 protein_coding Danio_rerio 0 331
ENST00000263334 PAX8-201 protein_coding Homo_sapiens 0 2091
ENST00000263335 PAX8-002 protein_coding Homo_sapiens 0 1083
ENST00000348715 PAX8-004 protein_coding Homo_sapiens 0 1221
ENST00000355243 PAX2-001 protein_coding Homo_sapiens 0 333
ENST00000361791 PAX2-006 protein_coding Homo_sapiens 0 333
ENST00000370296 PAX2-002 protein_coding Homo_sapiens 0 333
ENST00000397647 PAX8-003 protein_coding Homo_sapiens 0 1081
ENST00000427256 PAX2-003 protein_coding Homo_sapiens 0 333
ENST00000428433 PAX2-201 protein_coding Homo_sapiens 0 333
ENST00000429538 PAX8-001 protein_coding Homo_sapiens 0 2159
ENST00000465084 PAX8-009 protein_coding Homo_sapiens 0 492
ENST00000467778 PAX8-007 retained_intron Homo_sapiens 0 1090
ENST00000468980 PAX8-006 protein_coding Homo_sapiens 0 398
ENST00000485840 PAX8-005 retained_intron Homo_sapiens 0 547
ENST00000497038 PAX8-008 nonsense_mediated_decay Homo_sapiens 0 994
ENST00000554172 PAX2-005 protein_coding Homo_sapiens 0 333
ENST00000554352 PAX8-013 retained_intron Homo_sapiens 0 381
ENST00000554830 PAX8-012 protein_coding Homo_sapiens 0 488

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