C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: trans-acting transcription factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027109 Sp3 10090 - 2:72936427-72980446 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066003 Sp3-002 72936648-72980426 protein_coding
  ENSMUST00000102689 Sp3-001 72936427-72980446 protein_coding
  ENSMUST00000129565 Sp3-005 72938280-72941084 processed_transcript
  ENSMUST00000133615 Sp3-003 72936652-72979286 processed_transcript
  ENSMUST00000141372 Sp3-004 72946396-72970466 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066003ENSMUST00000102689ENSMUST00000133615ENSMUST00000141372
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066003 N/A N/A 2.480±0.00 2.309±1.22 3.876±1.06 N/A 2.208±1.03 1.093±0.00 3.503±1.55 N/A 1.385±0.39 2.848±0.00 10.230±3.88 N/A
ENSMUST00000102689 2.729±0.00 N/A 4.546±0.75 6.572±0.66 4.393±0.00 3.931±0.86 1.219±0.24 2.333±0.96 4.014±1.97 5.285±0.19 2.900±0.27 5.911±2.33 5.494±2.04 0.809±0.54
ENSMUST00000133615 9.815±3.11 14.491±1.07 5.122±0.00 4.013±3.14 9.489±5.02 10.641±0.63 2.080±0.95 4.276±1.55 6.019±3.98 8.749±0.26 1.824±0.53 11.867±5.26 7.731±3.50 2.227±1.28
ENSMUST00000141372 N/A N/A N/A 4.342±0.00 15.691±0.00 N/A N/A N/A N/A N/A N/A 15.545±0.00 18.924±0.00 4.574±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007OE CIL_0007OE_0002 UCNEbase 2:72378722-73287933
CIL_0004JD CIL_0004JD_0002 CGP 2:72476159-72980446
CIL_0008JW CIL_0008JW_0002 VISTA 2:72839371-73441413
CIL_0008K1 CIL_0008K1_0002 VISTA 2:72842671-73444272
CIL_0008S8 CIL_0008S8_0002 VISTA 2:72879758-73480791

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 IDA core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001503 IGI ossification
GO:0001701 IGI in utero embryonic development
GO:0001779 IMP natural killer cell differentiation
GO:0001829 IGI trophectodermal cell differentiation
GO:0001889 IGI liver development
GO:0001892 IGI embryonic placenta development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0017053 IDA transcriptional repressor complex
GO:0030183 IMP B cell differentiation
GO:0030217 IMP T cell differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030219 IGI megakaryocyte differentiation
GO:0030224 IMP monocyte differentiation
GO:0030324 IGI lung development
GO:0030851 IMP granulocyte differentiation
GO:0043353 IGI enucleate erythrocyte differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0048596 IGI embryonic camera-type eye morphogenesis
GO:0048706 IGI embryonic skeletal system development
GO:0060136 IGI embryonic process involved in female pregnancy
GO:0060216 IGI definitive hemopoiesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001549 sp3a sp3a transcription factor protein_coding Danio_rerio
ENSDARG00000007812 sp3b Sp3b transcription factor protein_coding Danio_rerio
ENSG00000172845 SP3 Sp3 transcription factor protein_coding Homo_sapiens

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