C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Sp3 transcription factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172845 SP3 9606 - 2:173906459-173965702 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310015 SP3-001 173906459-173965702 protein_coding
  ENST00000416195 SP3-002 173908530-173964553 protein_coding
  ENST00000418194 SP3-003 173908530-173964219 protein_coding
  ENST00000462904 SP3-007 173955817-173965310 processed_transcript
  ENST00000465379 SP3-004 173908532-173916832 retained_intron
  ENST00000483084 SP3-005 173956074-173963379 processed_transcript
  ENST00000490182 SP3-008 173956081-173964885 processed_transcript

Homo sapiens EnsemblGRCh38

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Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310015ENST00000416195ENST00000418194ENST00000465379
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310015 2.809±0.00 3.784±0.00 0.824±0.00 0.874±0.17 2.134±0.46 0.813±0.00 0.893±0.00 N/A 1.318±0.74 2.001±0.90 N/A 1.745±0.16 0.942±0.23 0.904±0.00
ENST00000416195 5.266±0.00 4.049±0.00 N/A 3.600±0.04 11.879±3.79 4.397±0.26 2.134±1.12 4.495±0.13 1.977±0.00 8.030±1.19 5.643±1.91 8.415±0.76 5.398±0.36 11.377±5.95
ENST00000418194 11.447±0.00 5.760±0.00 2.593±0.00 3.727±1.16 4.734±0.00 10.994±3.39 3.791±0.38 4.413±1.40 7.720±6.41 6.640±1.92 1.724±0.00 8.449±5.24 2.836±2.05 3.491±1.43
ENST00000465379 N/A N/A N/A N/A N/A 2.777±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007OE CIL_0007OE_0001 UCNEbase 2:173198009-174351945
CIL_0004JD CIL_0004JD_0001 CGP 2:173354820-173965702
CIL_0008JW CIL_0008JW_0001 VISTA 2:173820816-174422736
CIL_0008K1 CIL_0008K1_0001 VISTA 2:173824009-174425635
CIL_0008S8 CIL_0008S8_0001 VISTA 2:173876675-174477772
CIL_0003II CIL_0003II_0002 CGP 2:173906459-174248698

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 IEA core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001503 IEA ossification
GO:0001701 IEA in utero embryonic development
GO:0001779 IEA natural killer cell differentiation
GO:0001829 IEA trophectodermal cell differentiation
GO:0001889 IEA liver development
GO:0001892 IEA embryonic placenta development
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0017053 IEA transcriptional repressor complex
GO:0030183 IEA B cell differentiation
GO:0030217 IEA T cell differentiation
GO:0030218 IEA erythrocyte differentiation
GO:0030219 IEA megakaryocyte differentiation
GO:0030224 IEA monocyte differentiation
GO:0030324 IEA lung development
GO:0030851 IEA granulocyte differentiation
GO:0043353 IEA enucleate erythrocyte differentiation
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0048596 IEA embryonic camera-type eye morphogenesis
GO:0048706 IEA embryonic skeletal system development
GO:0060136 IEA embryonic process involved in female pregnancy
GO:0060216 IEA definitive hemopoiesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001549 sp3a sp3a transcription factor protein_coding Danio_rerio
ENSDARG00000007812 sp3b Sp3b transcription factor protein_coding Danio_rerio
ENSMUSG00000027109 Sp3 trans-acting transcription factor 3 protein_coding Mus_musculus

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