C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: jagged 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027276 Jag1 10090 - 2:137081456-137116644 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028735 Jag1-001 137081456-137116644 protein_coding
  ENSMUST00000133640 Jag1-002 137082893-137085949 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028735ENSMUST00000133640
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028735 7.297±0.40 2.243±0.26 3.637±1.54 1.476±0.94 3.992±1.98 2.811±0.67 1.380±0.67 3.250±0.68 0.303±0.09 7.096±0.45 1.073±0.52 6.737±1.06 1.728±0.70 2.357±1.05
ENSMUST00000133640 N/A N/A N/A 0.945±0.00 N/A N/A N/A N/A 0.258±0.02 N/A N/A 3.621±0.00 1.139±0.52 10.175±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043P CIL_00043P_0002 CGP 2:136891218-137116644
CIL_0009DB CIL_0009DB_0002 VISTA 2:136947708-137548975
CIL_000362 CIL_000362_0002 CGP 2:137081456-138589292

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001974 IMP blood vessel remodeling
GO:0002011 IMP morphogenesis of an epithelial sheet
GO:0002456 IEA T cell mediated immunity
GO:0003184 ISS pulmonary valve morphogenesis
GO:0003215 IMP cardiac right ventricle morphogenesis
GO:0005112 IPI Notch binding
GO:0005509 NAS calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007219 TAS Notch signaling pathway
GO:0009887 IMP organ morphogenesis
GO:0016021 IEA integral component of membrane
GO:0032495 IDA response to muramyl dipeptide
GO:0035909 IMP aorta morphogenesis
GO:0042491 IMP auditory receptor cell differentiation
GO:0043010 IMP camera-type eye development
GO:0045177 IDA apical part of cell
GO:0045596 IMP negative regulation of cell differentiation
GO:0045599 IDA negative regulation of fat cell differentiation
GO:0045639 IDA positive regulation of myeloid cell differentiation
GO:0045665 IMP negative regulation of neuron differentiation
GO:0045669 IDA positive regulation of osteoblast differentiation
GO:0045747 IDA positive regulation of Notch signaling pathway
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048839 IMP inner ear development
GO:0060411 IMP cardiac septum morphogenesis
GO:0061073 IMP ciliary body morphogenesis
GO:0061156 ISS pulmonary artery morphogenesis
GO:0061309 IMP cardiac neural crest cell development involved in outflow tract morphogenesis
GO:0061314 IMP Notch signaling involved in heart development
GO:0061444 IMP endocardial cushion cell development
GO:0072017 IEP distal tubule development
GO:0072070 IEP loop of Henle development
GO:0097150 IEA neuronal stem cell maintenance
GO:2000737 IEA negative regulation of stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013168 jag1b jagged 1b protein_coding Danio_rerio
ENSDARG00000030289 jag1a jagged 1a protein_coding Danio_rerio
ENSG00000101384 JAG1 jagged 1 protein_coding Homo_sapiens

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