C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: jagged 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101384 JAG1 9606 - 20:10637684-10674107 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254958 JAG1-002 10637684-10674107 protein_coding
  ENST00000423891 JAG1-004 10637759-10662506 processed_transcript
  ENST00000488480 JAG1-011 10644443-10646366 retained_intron
  ENST00000612857 JAG1-010 10645372-10647312 retained_intron
  ENST00000613518 JAG1-003 10645722-10648028 protein_coding
  ENST00000617357 JAG1-013 10639870-10641276 retained_intron
  ENST00000617965 JAG1-007 10651233-10652722 retained_intron
  ENST00000620743 JAG1-009 10647981-10649588 retained_intron
  ENST00000622545 JAG1-008 10647048-10650257 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254958ENST00000423891
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254958 19.326±0.00 12.340±0.00 1.900±0.00 2.442±1.08 8.440±1.72 10.427±4.41 3.533±1.17 4.611±4.23 4.842±4.35 13.379±7.32 4.119±0.00 6.632±1.42 21.621±13.40 5.228±3.86
ENST00000423891 N/A N/A N/A N/A N/A N/A N/A N/A 0.347±0.00 1.445±0.00 1.060±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043P CIL_00043P_0001 CGP 20:10435303-10674107
CIL_0009DB CIL_0009DB_0001 VISTA 20:10512535-11113791
CIL_000362 CIL_000362_0001 CGP 20:10637684-11926609

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 NAS angiogenesis
GO:0001709 NAS cell fate determination
GO:0001974 IEA blood vessel remodeling
GO:0002011 IEA morphogenesis of an epithelial sheet
GO:0002456 IMP T cell mediated immunity
GO:0003184 IMP pulmonary valve morphogenesis
GO:0003215 ISS cardiac right ventricle morphogenesis
GO:0005112 NAS Notch binding
GO:0005198 NAS structural molecule activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 NAS extracellular region
GO:0005886 IDA plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0007154 IEA cell communication
GO:0007219 IMP:IEA Notch signaling pathway
GO:0007220 TAS Notch receptor processing
GO:0007275 IEA multicellular organismal development
GO:0007399 NAS nervous system development
GO:0008083 NAS growth factor activity
GO:0009887 IEA organ morphogenesis
GO:0016020 TAS:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030097 NAS hemopoiesis
GO:0030216 NAS keratinocyte differentiation
GO:0030334 NAS regulation of cell migration
GO:0032495 IEA response to muramyl dipeptide
GO:0035909 ISS aorta morphogenesis
GO:0042127 NAS regulation of cell proliferation
GO:0042491 IEA auditory receptor cell differentiation
GO:0043010 IEA camera-type eye development
GO:0045177 IEA apical part of cell
GO:0045445 NAS myoblast differentiation
GO:0045446 NAS endothelial cell differentiation
GO:0045596 IEA negative regulation of cell differentiation
GO:0045599 IEA negative regulation of fat cell differentiation
GO:0045639 IEA positive regulation of myeloid cell differentiation
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045747 IEA positive regulation of Notch signaling pathway
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048839 IEA inner ear development
GO:0060411 ISS cardiac septum morphogenesis
GO:0061073 IEA ciliary body morphogenesis
GO:0061156 IMP pulmonary artery morphogenesis
GO:0061309 ISS cardiac neural crest cell development involved in outflow tract morphogenesis
GO:0061314 IMP Notch signaling involved in heart development
GO:0061444 ISS endocardial cushion cell development
GO:0072017 IEA distal tubule development
GO:0072070 IEA loop of Henle development
GO:0097150 IEP neuronal stem cell maintenance
GO:2000737 IMP negative regulation of stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013168 jag1b jagged 1b protein_coding Danio_rerio
ENSDARG00000030289 jag1a jagged 1a protein_coding Danio_rerio
ENSMUSG00000027276 Jag1 jagged 1 protein_coding Mus_musculus

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