C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: endothelin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027524 Edn3 10090 + 2:174760619-174784042 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029030 Edn3-001 174760619-174784042 protein_coding
  ENSMUST00000137369 Edn3-003 174761052-174782585 retained_intron
  ENSMUST00000140908 Edn3-002 174760799-174781980 protein_coding
  ENSMUST00000162473 Edn3-004 174769922-174782540 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029030ENSMUST00000137369ENSMUST00000140908ENSMUST00000162473
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029030 0.579±0.05 4.091±0.31 1.750±0.23 0.926±0.38 0.063±0.02 1.559±0.33 0.088±0.06 1.428±0.16 0.089±0.05 4.973±0.09 0.332±0.08 1.604±0.62 0.277±0.15 0.185±0.15
ENSMUST00000137369 N/A N/A N/A N/A 0.018±0.00 0.769±0.21 N/A 0.530±0.09 0.011±0.00 1.112±0.00 0.207±0.00 0.862±0.29 0.129±0.03 0.024±0.01
ENSMUST00000140908 0.313±0.00 N/A N/A N/A N/A N/A 0.130±0.00 0.607±0.00 0.035±0.00 N/A N/A N/A 0.170±0.00 N/A
ENSMUST00000162473 0.023±0.00 N/A N/A N/A 0.061±0.00 N/A N/A N/A N/A N/A 0.086±0.00 N/A 0.041±0.00 0.023±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093L CIL_00093L_0002 VISTA 2:174556549-175160580
CIL_00074T CIL_00074T_0002 CGP 2:174643534-174784042

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001755 IMP neural crest cell migration
GO:0002690 IEA positive regulation of leukocyte chemotaxis
GO:0003100 IEA regulation of systemic arterial blood pressure by endothelin
GO:0005179 IEA hormone activity
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006874 IGI cellular calcium ion homeostasis
GO:0007166 IEA cell surface receptor signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0010460 IEA positive regulation of heart rate
GO:0010961 IGI cellular magnesium ion homeostasis
GO:0014826 IEA vein smooth muscle contraction
GO:0019229 IEA regulation of vasoconstriction
GO:0030072 IEA peptide hormone secretion
GO:0030182 IMP neuron differentiation
GO:0030318 IDA melanocyte differentiation
GO:0030334 IMP regulation of cell migration
GO:0030593 IEA neutrophil chemotaxis
GO:0042310 IEA vasoconstriction
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0045840 IEA positive regulation of mitosis
GO:0046887 IEA positive regulation of hormone secretion
GO:0048016 IEA inositol phosphate-mediated signaling
GO:0048070 IMP regulation of developmental pigmentation
GO:1901381 IGI positive regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070925 endothelin 3 protein_coding Danio_rerio
ENSDARG00000086669 edn3b endothelin 3b protein_coding Danio_rerio
ENSG00000124205 EDN3 endothelin 3 protein_coding Homo_sapiens

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