C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: endothelin 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000029030 Edn3-001 ENSMUSG00000027524 10090 + 2:174760619-174784042 protein_coding

Mus musculus EnsemblGRCm38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029030
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029030 0.579±0.05 4.091±0.31 1.750±0.23 0.926±0.38 0.063±0.02 1.559±0.33 0.088±0.06 1.428±0.16 0.089±0.05 4.973±0.09 0.332±0.08 1.604±0.62 0.277±0.15 0.185±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093L CIL_00093L_0002 VISTA 2:174556549-175160580
CIL_00074T CIL_00074T_0002 CGP 2:174643534-174784042

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001755 IMP neural crest cell migration
GO:0002690 IEA positive regulation of leukocyte chemotaxis
GO:0003100 IEA regulation of systemic arterial blood pressure by endothelin
GO:0005179 IEA hormone activity
GO:0005615 IEA extracellular space
GO:0006874 IGI cellular calcium ion homeostasis
GO:0007166 IEA cell surface receptor signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0010460 IEA positive regulation of heart rate
GO:0010961 IGI cellular magnesium ion homeostasis
GO:0014826 IEA vein smooth muscle contraction
GO:0019229 IEA regulation of vasoconstriction
GO:0030072 IEA peptide hormone secretion
GO:0030182 IMP neuron differentiation
GO:0030318 IDA melanocyte differentiation
GO:0030334 IMP regulation of cell migration
GO:0030593 IEA neutrophil chemotaxis
GO:0042310 IEA vasoconstriction
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0045840 IEA positive regulation of mitosis
GO:0046887 IEA positive regulation of hormone secretion
GO:0048016 IEA inositol phosphate-mediated signaling
GO:0048070 IMP regulation of developmental pigmentation
GO:1901381 IGI positive regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000311585 EDN3-002 protein_coding Homo_sapiens 0 562
ENST00000337938 EDN3-001 protein_coding Homo_sapiens 0 562
ENST00000371025 EDN3-004 protein_coding Homo_sapiens 0 411
ENST00000371028 EDN3-201 protein_coding Homo_sapiens 0 562
ENST00000395654 EDN3-003 protein_coding Homo_sapiens 0 411

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