C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 4, group A, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028341 Nr4a3 10090 + 4:48045153-48086447 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030025 Nr4a3-001 48045153-48086445 protein_coding
  ENSMUST00000133539 Nr4a3-003 48051248-48056739 processed_transcript
  ENSMUST00000153369 Nr4a3-004 48049114-48086447 protein_coding
  ENSMUST00000154186 Nr4a3-002 48045231-48050165 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030025ENSMUST00000133539ENSMUST00000153369ENSMUST00000154186
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030025 0.149±0.07 7.170±3.57 0.636±0.09 1.686±0.28 0.371±0.23 0.346±0.11 0.256±0.09 0.084±0.04 0.005±0.00 0.617±0.25 0.493±0.27 0.279±0.17 0.082±0.02 0.176±0.11
ENSMUST00000133539 0.129±0.00 10.295±2.56 N/A N/A 1.332±0.00 0.290±0.00 N/A 0.072±0.04 0.015±0.01 0.646±0.00 N/A 0.465±0.10 N/A 0.524±0.05
ENSMUST00000153369 0.164±0.00 N/A 0.331±0.05 0.779±0.00 0.354±0.17 N/A 0.109±0.00 0.123±0.00 0.008±0.00 N/A 0.240±0.10 0.426±0.51 0.102±0.06 0.048±0.00
ENSMUST00000154186 N/A N/A N/A N/A 0.839±0.00 0.327±0.00 N/A 0.117±0.05 0.016±0.01 N/A N/A 0.464±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007HI CIL_0007HI_0003 CGP 4:47474658-48086447
CIL_0007H8 CIL_0007H8_0003 CGP 4:48045153-48186507

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001707 IMP mesoderm formation
GO:0003677 IEA DNA binding
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005667 IDA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0007411 IMP axon guidance
GO:0008270 IEA zinc ion binding
GO:0021766 IMP hippocampus development
GO:0030522 IEA intracellular receptor signaling pathway
GO:0030534 IMP adult behavior
GO:0031100 IEA organ regeneration
GO:0042472 IMP inner ear morphogenesis
GO:0042542 IMP response to hydrogen peroxide
GO:0043066 IMP negative regulation of apoptotic process
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043434 IEA response to peptide hormone
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0045787 IMP positive regulation of cell cycle
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048752 IMP semicircular canal morphogenesis
GO:0050885 IMP neuromuscular process controlling balance
GO:0060005 IMP vestibular reflex
GO:2000108 IMP positive regulation of leukocyte apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055854 nr4a3 nuclear receptor subfamily 4, group A, member 3 protein_coding Danio_rerio
ENSG00000119508 NR4A3 nuclear receptor subfamily 4, group A, member 3 protein_coding Homo_sapiens

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