C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain GRB2-like (endophilin) interacting protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028524 Sgip1 10090 + 4:102741297-102973628 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066824 Sgip1-001 102760135-102971983 protein_coding
  ENSMUST00000072481 Sgip1-006 102760345-102971863 protein_coding
  ENSMUST00000080728 Sgip1-004 102760363-102971177 protein_coding
  ENSMUST00000097948 Sgip1-012 102741297-102870826 protein_coding
  ENSMUST00000106882 Sgip1-007 102760525-102973628 protein_coding
  ENSMUST00000131431 Sgip1-014 102921295-102928739 processed_transcript
  ENSMUST00000136164 Sgip1-008 102760355-102861152 processed_transcript
  ENSMUST00000137592 Sgip1-009 102760328-102863716 processed_transcript
  ENSMUST00000140289 Sgip1-010 102760375-102870121 processed_transcript
  ENSMUST00000140676 Sgip1-015 102962356-102967914 processed_transcript
  ENSMUST00000141624 Sgip1-013 102927190-102928912 processed_transcript
  ENSMUST00000142430 Sgip1-003 102759222-102883347 processed_transcript
  ENSMUST00000149547 Sgip1-005 102870564-102970603 protein_coding
  ENSMUST00000156596 Sgip1-011 102760352-102869808 protein_coding
  ENSMUST00000183855 Sgip1-002 102760465-102919120 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENSMUST00000066824ENSMUST00000072481ENSMUST00000080728ENSMUST00000106882ENSMUST00000131431ENSMUST00000140676ENSMUST00000141624ENSMUST00000142430ENSMUST00000149547ENSMUST00000156596ENSMUST00000183855
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000066824 N/A N/A N/A 4.804±1.53 N/A N/A N/A N/A N/A 0.516±0.00 N/A N/A N/A
ENSMUST00000072481 0.153±0.00 N/A N/A N/A N/A N/A N/A N/A 0.050±0.00 0.999±0.00 N/A 0.087±0.00 N/A
ENSMUST00000080728 0.218±0.07 0.445±0.04 N/A 9.860±0.00 0.190±0.03 0.587±0.03 N/A N/A N/A 0.907±0.04 N/A 0.130±0.04 1.891±0.14
ENSMUST00000106882 0.081±0.00 0.204±0.00 0.242±0.00 N/A 0.139±0.00 0.308±0.12 N/A N/A N/A 0.609±0.15 0.129±0.01 N/A N/A
ENSMUST00000131431 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.231±0.00 N/A
ENSMUST00000140676 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.682±0.05 N/A
ENSMUST00000141624 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.495±0.00 N/A
ENSMUST00000142430 0.760±0.42 0.764±0.26 2.701±0.00 10.654±7.41 1.181±0.00 1.016±0.30 0.369±0.00 1.855±1.37 1.496±0.98 1.972±1.19 1.031±0.51 1.113±1.71 1.219±0.19
ENSMUST00000149547 0.526±0.29 N/A N/A 31.393±0.00 0.312±0.00 0.410±0.00 N/A 0.406±0.00 N/A 1.106±0.09 N/A 0.314±0.00 1.274±0.33
ENSMUST00000156596 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 57.560±0.00
ENSMUST00000183855 N/A N/A N/A N/A N/A N/A N/A N/A 0.127±0.00 N/A N/A N/A 2.582±0.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NS CIL_0002NS_0002 CGP 4:102087543-102973628
CIL_000262 CIL_000262_0002 CGP 4:102741297-103005594

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002021 ISS response to dietary excess
GO:0005515 IPI protein binding
GO:0005543 IDA phospholipid binding
GO:0005737 ISS cytoplasm
GO:0005886 IDA plasma membrane
GO:0005905 IEA coated pit
GO:0006897 IEA endocytosis
GO:0008017 IDA microtubule binding
GO:0015631 IPI tubulin binding
GO:0017124 IEA SH3 domain binding
GO:0030122 IDA AP-2 adaptor complex
GO:0030136 IDA clathrin-coated vesicle
GO:0048260 IMP positive regulation of receptor-mediated endocytosis
GO:0097320 IDA membrane tubulation
GO:2000253 ISS positive regulation of feeding behavior
GO:2000507 ISS positive regulation of energy homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077269 SGIP1 (1 of 2) SH3-domain GRB2-like (endophilin) interacting protein 1 protein_coding Danio_rerio
ENSDARG00000097897 SGIP1 (2 of 2) SH3-domain GRB2-like (endophilin) interacting protein 1 protein_coding Danio_rerio
ENSG00000118473 SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 protein_coding Homo_sapiens

Loading