C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain GRB2-like (endophilin) interacting protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118473 SGIP1 9606 + 1:66533383-66748299 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237247 SGIP1-002 66533383-66744374 protein_coding
  ENST00000320161 SGIP1-011 66695051-66704509 processed_transcript
  ENST00000371037 SGIP1-001 66534282-66748299 protein_coding
  ENST00000371039 SGIP1-003 66533592-66745085 protein_coding
  ENST00000424320 SGIP1-006 66533615-66679742 protein_coding
  ENST00000435165 SGIP1-004 66694694-66745084 protein_coding
  ENST00000468286 SGIP1-007 66534156-66677096 processed_transcript
  ENST00000468570 SGIP1-012 66695433-66704757 processed_transcript
  ENST00000480548 SGIP1-013 66670995-66690531 processed_transcript
  ENST00000483060 SGIP1-010 66625848-66644012 processed_transcript
  ENST00000484988 SGIP1-009 66615939-66626105 processed_transcript
  ENST00000487507 SGIP1-014 66682294-66690531 processed_transcript
  ENST00000493564 SGIP1-005 66533605-66626043 processed_transcript
  ENST00000497055 SGIP1-008 66534181-66626060 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000237247ENST00000371037ENST00000371039ENST00000424320ENST00000435165ENST00000468286ENST00000480548ENST00000483060
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000237247 N/A 0.436±0.00 N/A 2.970±0.29 N/A N/A 0.275±0.00 0.379±0.00 N/A 0.843±0.00 N/A N/A N/A N/A
ENST00000371037 N/A N/A N/A N/A 0.257±0.19 N/A 0.145±0.00 N/A 0.085±0.00 N/A N/A 0.109±0.00 0.021±0.00 0.171±0.00
ENST00000371039 0.234±0.00 N/A N/A 2.723±0.00 0.156±0.00 0.528±0.00 0.272±0.00 0.241±0.00 0.038±0.00 0.818±0.00 0.138±0.00 0.232±0.04 0.087±0.03 0.653±0.00
ENST00000424320 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.515±0.00 N/A 0.544±0.00 0.121±0.00 N/A
ENST00000435165 N/A 0.312±0.00 0.495±0.00 N/A 1.027±0.00 N/A 0.391±0.00 0.295±0.18 N/A 0.824±0.00 N/A 0.253±0.15 N/A 0.768±0.00
ENST00000468286 N/A N/A 1.874±0.00 13.059±0.00 3.373±0.00 N/A N/A N/A N/A 3.338±0.00 0.267±0.00 0.706±0.06 N/A 2.271±0.00
ENST00000480548 N/A N/A N/A N/A N/A N/A N/A N/A 1.266±0.00 N/A N/A N/A N/A N/A
ENST00000483060 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.126±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NS CIL_0002NS_0001 CGP 1:65792514-66748299
CIL_000262 CIL_000262_0001 CGP 1:66533383-66778787

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002021 ISS response to dietary excess
GO:0005515 IPI:IEA protein binding
GO:0005543 ISS phospholipid binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005905 IDA coated pit
GO:0006886 IEA intracellular protein transport
GO:0006897 IEA endocytosis
GO:0008017 ISS microtubule binding
GO:0015631 IEA tubulin binding
GO:0016192 IEA vesicle-mediated transport
GO:0017124 IPI SH3 domain binding
GO:0030122 ISS AP-2 adaptor complex
GO:0030131 IEA clathrin adaptor complex
GO:0030136 ISS clathrin-coated vesicle
GO:0048260 ISS positive regulation of receptor-mediated endocytosis
GO:0097320 IEA membrane tubulation
GO:2000253 ISS positive regulation of feeding behavior
GO:2000507 ISS positive regulation of energy homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077269 SGIP1 (1 of 2) SH3-domain GRB2-like (endophilin) interacting protein 1 protein_coding Danio_rerio
ENSDARG00000097897 SGIP1 (2 of 2) SH3-domain GRB2-like (endophilin) interacting protein 1 protein_coding Danio_rerio
ENSMUSG00000028524 Sgip1 SH3-domain GRB2-like (endophilin) interacting protein 1 protein_coding Mus_musculus

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