C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leprecan 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028641 Lepre1 10090 + 4:119232915-119248975 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030393 Lepre1-012 119232939-119248975 protein_coding
  ENSMUST00000081606 Lepre1-007 119233832-119248973 protein_coding
  ENSMUST00000102662 Lepre1-003 119232946-119248972 protein_coding
  ENSMUST00000121111 Lepre1-001 119232915-119248972 protein_coding
  ENSMUST00000123963 Lepre1-011 119237942-119244149 processed_transcript
  ENSMUST00000126056 Lepre1-006 119233800-119236932 processed_transcript
  ENSMUST00000127087 Lepre1-009 119246862-119248054 retained_intron
  ENSMUST00000131875 Lepre1-005 119235344-119241495 processed_transcript
  ENSMUST00000134548 Lepre1-008 119246639-119248372 processed_transcript
  ENSMUST00000136278 Lepre1-004 119232954-119248369 nonsense_mediated_decay
  ENSMUST00000142361 Lepre1-010 119245020-119248133 processed_transcript
  ENSMUST00000153940 Lepre1-002 119232946-119248367 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030393ENSMUST00000081606ENSMUST00000102662ENSMUST00000121111ENSMUST00000123963ENSMUST00000127087ENSMUST00000131875ENSMUST00000134548ENSMUST00000136278ENSMUST00000153940
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030393 N/A N/A N/A N/A N/A N/A N/A 1.729±0.43 1.489±0.00 N/A N/A 9.605±2.58 N/A N/A
ENSMUST00000081606 N/A N/A N/A N/A 1.289±0.00 N/A N/A N/A N/A N/A 1.044±0.00 15.521±1.38 N/A N/A
ENSMUST00000102662 N/A N/A N/A N/A 2.061±0.00 N/A N/A N/A N/A N/A N/A 5.226±0.00 10.031±0.00 0.570±0.00
ENSMUST00000121111 19.593±2.56 19.112±2.72 12.930±1.45 7.494±1.02 10.632±1.39 4.842±1.36 5.956±0.74 6.973±1.03 7.396±2.51 10.740±1.42 2.709±0.30 33.000±12.23 16.372±3.63 4.960±0.35
ENSMUST00000123963 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.031±0.00
ENSMUST00000127087 N/A N/A N/A 2.088±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000131875 N/A N/A N/A N/A 8.836±0.00 N/A N/A N/A N/A N/A N/A N/A 34.864±6.54 N/A
ENSMUST00000134548 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.019±0.00 N/A 14.416±0.00 N/A
ENSMUST00000136278 N/A 4.494±0.00 N/A 0.956±0.28 N/A 0.722±0.00 N/A N/A 1.606±0.00 N/A N/A 6.503±0.00 N/A N/A
ENSMUST00000153940 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.412±0.00 8.439±2.11 0.972±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008N2 CIL_0008N2_0002 VISTA 4:118719151-119320076
CIL_0008PM CIL_0008PM_0002 VISTA 4:118938785-119540197

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 ISO endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0006457 IEA protein folding
GO:0016020 IEA membrane
GO:0016049 IDA cell growth
GO:0018126 IEA protein hydroxylation
GO:0019511 ISO peptidyl-proline hydroxylation
GO:0019797 ISO procollagen-proline 3-dioxygenase activity
GO:0030199 IMP collagen fibril organization
GO:0030278 IMP regulation of ossification
GO:0031418 IEA L-ascorbic acid binding
GO:0032963 ISO collagen metabolic process
GO:0050708 IEA regulation of protein secretion
GO:0050821 IEA protein stabilization
GO:0055114 IEA oxidation-reduction process
GO:0060348 IEA bone development
GO:0070062 IEA extracellular vesicular exosome
GO:1901874 IEA negative regulation of post-translational protein modification

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071212 lepre1 leucine proline-enriched proteoglycan (leprecan) 1 protein_coding Danio_rerio
ENSG00000117385 LEPRE1 leucine proline-enriched proteoglycan (leprecan) 1 protein_coding Homo_sapiens

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