C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029247 Paics 10090 + 5:76951307-76967509 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031160 Paics-003 76951307-76967505 protein_coding
  ENSMUST00000117536 Paics-002 76951368-76967313 protein_coding
  ENSMUST00000120912 Paics-001 76951348-76967509 protein_coding
  ENSMUST00000140051 Paics-006 76961476-76962970 retained_intron
  ENSMUST00000141687 Paics-004 76951382-76959350 protein_coding
  ENSMUST00000153648 Paics-005 76951777-76962479 nonsense_mediated_decay
  ENSMUST00000154688 Paics-007 76966157-76966841 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031160ENSMUST00000117536ENSMUST00000120912ENSMUST00000154688
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031160 11.481±2.13 16.408±2.41 11.643±2.44 13.154±4.09 7.037±2.12 5.342±0.68 10.241±2.76 8.347±0.00 14.522±5.30 4.115±0.44 13.387±2.19 7.300±1.02 12.311±4.04 3.966±0.33
ENSMUST00000117536 14.425±6.69 14.310±0.43 13.847±2.31 19.148±12.99 13.907±2.04 11.724±4.02 16.442±2.12 46.643±4.77 44.214±25.60 18.363±2.75 11.661±1.51 26.664±17.79 33.207±16.44 12.525±8.48
ENSMUST00000120912 8.069±0.62 N/A 17.340±0.46 12.212±2.79 5.062±0.00 N/A 32.006±0.00 N/A 34.471±6.96 12.912±0.00 9.023±2.97 29.045±9.94 20.656±9.35 7.291±1.58
ENSMUST00000154688 N/A 41.141±5.75 N/A N/A N/A 17.322±2.02 N/A N/A N/A N/A N/A 31.314±4.97 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084Q CIL_00084Q_0002 VISTA 5:76362343-76966797
CIL_0008G9 CIL_0008G9_0002 VISTA 5:76829880-77430993
CIL_00025Q CIL_00025Q_0002 CGP 5:76873659-76951578
CIL_0001WN CIL_0001WN_0002 CGP 5:76913249-76967509
CIL_0001WO CIL_0001WO_0002 CGP 5:76951307-76999937

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004638 IEA phosphoribosylaminoimidazole carboxylase activity
GO:0004639 IEA phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0016020 IEA membrane
GO:0042802 IEA identical protein binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033539 paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase protein_coding Danio_rerio
ENSG00000128050 PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase protein_coding Homo_sapiens

Loading