C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128050 PAICS 9606 + 4:56435741-56461368 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264221 PAICS-201 56435749-56461368 protein_coding
  ENST00000399688 PAICS-003 56436138-56461361 protein_coding
  ENST00000504188 PAICS-009 56436039-56441863 retained_intron
  ENST00000505164 PAICS-001 56435752-56459499 protein_coding
  ENST00000508554 PAICS-010 56448699-56451191 retained_intron
  ENST00000510584 PAICS-008 56436138-56442028 retained_intron
  ENST00000512576 PAICS-006 56436152-56459664 protein_coding
  ENST00000514888 PAICS-002 56435741-56461361 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264221ENST00000399688ENST00000505164ENST00000512576ENST00000514888
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264221 1.408±0.00 N/A 1.849±0.00 6.054±0.00 N/A 4.734±0.00 0.225±0.00 N/A 6.449±6.07 N/A N/A 6.356±0.94 8.934±3.66 3.159±0.00
ENST00000399688 4.026±0.00 6.138±0.00 N/A 6.675±0.00 6.203±0.00 3.156±0.00 1.818±0.00 9.978±0.00 5.290±0.00 N/A N/A 11.433±8.45 5.228±2.22 10.832±1.64
ENST00000505164 N/A N/A N/A N/A N/A N/A N/A N/A 1.839±0.00 N/A N/A 22.913±0.00 17.159±0.00 10.117±0.00
ENST00000512576 3.296±0.00 N/A N/A N/A 2.958±0.16 4.814±0.28 0.967±0.00 N/A N/A 1.971±0.00 2.181±0.48 6.714±1.39 N/A 3.663±0.00
ENST00000514888 N/A N/A 1.730±0.00 5.741±0.00 N/A 5.417±0.00 2.873±0.00 6.476±0.00 0.383±0.00 N/A N/A 8.033±5.63 4.962±0.22 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001WN CIL_0001WN_0001 CGP 4:56393362-56461368
CIL_0008G9 CIL_0008G9_0001 VISTA 4:56396035-56999166
CIL_0001WO CIL_0001WO_0001 CGP 4:56435741-56503680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004638 TAS phosphoribosylaminoimidazole carboxylase activity
GO:0004639 IEA:TAS phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0009113 TAS purine nucleobase biosynthetic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0016020 IDA membrane
GO:0042802 IPI identical protein binding
GO:0044281 TAS small molecule metabolic process
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033539 paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase protein_coding Danio_rerio
ENSMUSG00000029247 Paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase protein_coding Mus_musculus

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