C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029491 Pde6b 10090 + 5:108388391-108432397 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031456 Pde6b-001 108388391-108431743 protein_coding
  ENSMUST00000130448 Pde6b-003 108430377-108432397 retained_intron
  ENSMUST00000134865 Pde6b-002 108388426-108431667 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031456ENSMUST00000130448ENSMUST00000134865
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031456 N/A N/A N/A 0.071±0.00 N/A N/A N/A N/A 0.009±0.00 0.018±0.00 0.016±0.00 0.074±0.01 0.020±0.00 0.013±0.00
ENSMUST00000130448 0.162±0.00 0.126±0.01 0.019±0.01 0.057±0.03 0.087±0.05 0.208±0.08 0.122±0.05 0.141±0.06 0.048±0.02 0.090±0.03 0.039±0.00 0.338±0.19 0.031±0.00 0.051±0.02
ENSMUST00000134865 0.028±0.02 0.068±0.03 0.003±0.00 0.005±0.00 0.038±0.02 0.046±0.03 0.009±0.00 0.027±0.01 0.016±0.01 0.028±0.02 0.013±0.00 0.071±0.04 0.012±0.01 0.016±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070Z CIL_00070Z_0003 CGP 5:108388391-108434448

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005886 TAS plasma membrane
GO:0007165 IEA signal transduction
GO:0007601 IEA visual perception
GO:0009583 IMP detection of light stimulus
GO:0046037 IEA GMP metabolic process
GO:0046872 IEA metal ion binding
GO:0047555 IEA 3',5'-cyclic-GMP phosphodiesterase activity
GO:0051480 IEA cytosolic calcium ion homeostasis
GO:0060041 IMP retina development in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011671 pde6b phosphodiesterase 6B, cGMP-specific, rod, beta protein_coding Danio_rerio
ENSG00000133256 PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta protein_coding Homo_sapiens

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