C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphodiesterase 6B, cGMP-specific, rod, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133256 PDE6B 9606 + 4:625584-670782 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000255622 PDE6B-001 625584-670782 protein_coding
  ENST00000429163 PDE6B-003 653180-670233 protein_coding
  ENST00000460119 PDE6B-010 663723-664922 retained_intron
  ENST00000461490 PDE6B-012 664910-670314 protein_coding
  ENST00000465426 PDE6B-007 651559-654858 protein_coding
  ENST00000467152 PDE6B-004 653211-654374 retained_intron
  ENST00000471824 PDE6B-011 663770-670193 protein_coding
  ENST00000474251 PDE6B-005 651985-654288 retained_intron
  ENST00000476034 PDE6B-009 652273-654669 retained_intron
  ENST00000487902 PDE6B-006 651985-656943 protein_coding
  ENST00000488061 PDE6B-008 653177-654084 protein_coding
  ENST00000496514 PDE6B-002 625606-670753 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000255622ENST00000429163ENST00000460119ENST00000461490ENST00000471824ENST00000496514
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000255622 N/A N/A 1.592±0.00 N/A N/A N/A N/A 0.026±0.00 N/A N/A N/A N/A 0.306±0.00
ENST00000429163 N/A N/A 4.767±0.00 0.210±0.00 N/A N/A N/A N/A 0.259±0.17 N/A 0.443±0.30 0.136±0.00 N/A
ENST00000460119 N/A N/A N/A N/A N/A 0.829±0.00 N/A N/A N/A 0.121±0.00 3.303±2.56 1.938±1.37 N/A
ENST00000461490 N/A N/A N/A 0.712±0.00 N/A 0.179±0.00 1.379±0.00 1.091±0.00 1.705±0.00 0.149±0.00 3.861±0.00 1.103±0.69 9.614±0.00
ENST00000471824 3.178±0.00 0.244±0.00 N/A N/A 0.715±0.00 0.087±0.00 N/A N/A 0.961±0.00 N/A 1.078±0.00 1.353±0.15 N/A
ENST00000496514 N/A N/A 0.652±0.00 N/A N/A N/A 0.105±0.00 0.112±0.00 N/A 0.007±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070Z CIL_00070Z_0002 CGP 4:625584-674338

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004114 IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0007165 IEA signal transduction
GO:0007601 IEA visual perception
GO:0007603 TAS phototransduction, visible light
GO:0008152 IEA metabolic process
GO:0009583 IEA detection of light stimulus
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0046037 IMP GMP metabolic process
GO:0046872 IEA metal ion binding
GO:0047555 IMP 3',5'-cyclic-GMP phosphodiesterase activity
GO:0051480 IMP cytosolic calcium ion homeostasis
GO:0060041 IEA retina development in camera-type eye
GO:0097381 TAS photoreceptor disc membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011671 pde6b phosphodiesterase 6B, cGMP-specific, rod, beta protein_coding Danio_rerio
ENSMUSG00000029491 Pde6b phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide protein_coding Mus_musculus

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