C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030265 Kras 10090 - 6:145216699-145250239 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032399 Kras-001 145216699-145250239 protein_coding
  ENSMUST00000111710 Kras-002 145220245-145250177 protein_coding
  ENSMUST00000123972 Kras-005 145219980-145230824 processed_transcript
  ENSMUST00000149314 Kras-004 145220610-145225557 retained_intron
  ENSMUST00000155145 Kras-003 145246704-145250202 protein_coding
  ENSMUST00000156486 Kras-006 145220297-145250170 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032399ENSMUST00000111710ENSMUST00000123972ENSMUST00000156486
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032399 6.327±1.53 2.835±0.65 10.489±1.14 26.116±1.57 5.634±1.35 15.831±5.66 5.290±0.93 6.565±1.34 10.361±4.95 16.339±2.74 3.491±0.45 7.759±1.51 12.115±6.15 2.900±1.11
ENSMUST00000111710 N/A N/A N/A 14.291±0.00 N/A N/A N/A N/A N/A N/A N/A 9.209±0.00 16.040±3.20 4.923±0.00
ENSMUST00000123972 N/A N/A N/A N/A 9.036±1.04 21.338±0.00 N/A N/A N/A 20.044±1.45 N/A 15.108±2.39 N/A 6.249±0.83
ENSMUST00000156486 N/A N/A N/A 18.888±0.00 N/A N/A N/A N/A N/A N/A N/A 10.819±0.00 16.293±0.33 8.263±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XB CIL_0008XB_0002 VISTA 6:144644642-145246014
CIL_0004XD CIL_0004XD_0002 CGP 6:145174834-145216939
CIL_0006UC CIL_0006UC_0002 CGP 6:145211134-145250239
CIL_0004X7 CIL_0004X7_0002 CGP 6:145216699-145614319

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0003924 TAS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005739 IEA mitochondrion
GO:0005886 TAS plasma membrane
GO:0005925 IEA focal adhesion
GO:0006184 IEA GTP catabolic process
GO:0007265 TAS Ras protein signal transduction
GO:0008284 IGI positive regulation of cell proliferation
GO:0008542 IGI visual learning
GO:0010628 IEA positive regulation of gene expression
GO:0016020 IDA membrane
GO:0019002 IEA GMP binding
GO:0019003 IEA GDP binding
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0030036 IGI actin cytoskeleton organization
GO:0030275 IEA LRR domain binding
GO:0032228 IGI regulation of synaptic transmission, GABAergic
GO:0032403 ISO protein complex binding
GO:0035022 IGI positive regulation of Rac protein signal transduction
GO:0035176 IEA social behavior
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0045121 IEA membrane raft
GO:0045596 IDA negative regulation of cell differentiation
GO:0048169 IGI regulation of long-term neuronal synaptic plasticity
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0051146 IGI striated muscle cell differentiation
GO:0051384 IEA response to glucocorticoid
GO:0051385 IEA response to mineralocorticoid
GO:0060441 IDA epithelial tube branching involved in lung morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000133703 KRAS Kirsten rat sarcoma viral oncogene homolog protein_coding Homo_sapiens

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