C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 5B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030313 Dennd5b 10090 - 6:148988071-149101680 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000111557 Dennd5b-001 148988071-149101680 protein_coding
  ENSMUST00000127727 Dennd5b-003 149068580-149101584 protein_coding
  ENSMUST00000129539 Dennd5b-005 149013850-149017188 retained_intron
  ENSMUST00000145555 Dennd5b-004 149068557-149081295 protein_coding
  ENSMUST00000150436 Dennd5b-002 149013988-149101538 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000111557ENSMUST00000127727ENSMUST00000150436
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000111557 0.877±0.14 0.461±0.10 0.663±0.06 3.784±0.73 0.707±0.20 0.533±0.17 0.652±0.33 1.300±0.49 3.136±1.63 1.298±0.32 0.351±0.20 0.785±0.25 1.292±0.88 0.967±0.09
ENSMUST00000127727 N/A 3.167±1.11 N/A N/A 3.242±0.59 2.026±0.59 N/A 2.503±0.00 5.986±0.63 2.494±0.00 N/A 3.429±0.97 N/A N/A
ENSMUST00000150436 0.849±0.24 0.540±0.08 N/A 8.378±0.00 0.991±0.33 0.765±0.22 0.559±0.13 1.185±0.09 3.201±0.77 1.069±0.00 N/A 1.515±0.70 1.107±0.26 1.741±0.47

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003DK CIL_0003DK_0003 CGP 6:148921035-149101680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0016020 IBA membrane
GO:0016021 IEA integral component of membrane
GO:0017112 IBA:ISS Rab guanyl-nucleotide exchange factor activity
GO:0032851 IBA:ISS positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003789 dennd5b DENN/MADD domain containing 5B protein_coding Danio_rerio
ENSG00000170456 DENND5B DENN/MADD domain containing 5B protein_coding Homo_sapiens

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