C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mcf.2 transforming sequence
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031139 Mcf2 10090 - X:60055956-60179089 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033478 Mcf2-002 60055959-60147643 protein_coding
  ENSMUST00000063507 Mcf2-001 60055956-60179089 protein_coding
  ENSMUST00000101531 Mcf2-003 60055956-60147700 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033478ENSMUST00000063507ENSMUST00000101531
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033478 N/A 0.073±0.00 0.003±0.00 0.048±0.00 0.042±0.00 N/A 0.013±0.00 0.019±0.01 N/A N/A 0.184±0.10 N/A 0.330±0.00
ENSMUST00000063507 0.089±0.00 N/A N/A N/A 0.041±0.00 0.009±0.00 0.013±0.00 0.014±0.00 0.013±0.00 0.005±0.00 0.250±0.10 N/A 0.530±0.34
ENSMUST00000101531 N/A N/A 0.001±0.00 0.477±0.35 N/A N/A 0.002±0.00 0.000±0.00 N/A N/A N/A 0.007±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000PO CIL_0000PO_0003 CGP X:59999464-60179089
CIL_0000PN CIL_0000PN_0003 CGP X:60055956-60592698

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0016358 IMP dendrite development
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0043547 TAS positive regulation of GTPase activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022895 mcf2a MCF.2 cell line derived transforming sequence a protein_coding Danio_rerio
ENSDARG00000056603 mcf2b MCF.2 cell line derived transforming sequence b protein_coding Danio_rerio
ENSG00000101977 MCF2 MCF.2 cell line derived transforming sequence protein_coding Homo_sapiens

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