C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031429 Psmd10 10090 - X:140948429-140956728 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033805 Psmd10-001 140948429-140956689 protein_coding
  ENSMUST00000112978 Psmd10-002 140948429-140956728 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033805ENSMUST00000112978
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033805 3.390±0.50 1.784±0.37 6.341±0.46 3.789±1.77 3.067±1.00 3.864±0.43 2.885±0.44 5.348±1.03 7.555±5.19 3.075±0.44 3.496±0.61 3.825±2.87 7.777±3.43 4.192±1.60
ENSMUST00000112978 1.081±0.37 0.509±0.00 2.249±0.13 2.429±0.35 1.004±0.54 0.682±0.10 0.792±0.00 1.220±0.50 1.736±1.26 1.334±0.55 0.657±0.18 1.647±0.80 3.055±1.22 1.345±0.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JJ CIL_0006JJ_0002 CGP X:140907608-140956728
CIL_0006JI CIL_0006JI_0002 CGP X:140948429-141164270

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000502 IEA proteasome complex
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006915 IEA apoptotic process
GO:0007253 ISS cytoplasmic sequestering of NF-kappaB
GO:0008134 IEA transcription factor binding
GO:0008540 IEA proteasome regulatory particle, base subcomplex
GO:0030307 ISS positive regulation of cell growth
GO:0031398 ISS positive regulation of protein ubiquitination
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0032436 ISS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043409 ISS negative regulation of MAPK cascade
GO:0043518 ISS negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045111 IEA intermediate filament cytoskeleton
GO:0045737 ISS positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0070682 ISS proteasome regulatory particle assembly
GO:0090201 ISS negative regulation of release of cytochrome c from mitochondria

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015628 psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 protein_coding Danio_rerio
ENSG00000101843 PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 protein_coding Homo_sapiens

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