C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033805 Psmd10-001 ENSMUSG00000031429 10090 - X:140948429-140956689 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033805
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033805 3.390±0.50 1.784±0.37 6.341±0.46 3.789±1.77 3.067±1.00 3.864±0.43 2.885±0.44 5.348±1.03 7.555±5.19 3.075±0.44 3.496±0.61 3.825±2.87 7.777±3.43 4.192±1.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JJ CIL_0006JJ_0002 CGP X:140907608-140956728
CIL_0006JI CIL_0006JI_0002 CGP X:140948429-141164270

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000502 IEA proteasome complex
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006915 IEA apoptotic process
GO:0007253 ISS cytoplasmic sequestering of NF-kappaB
GO:0008134 IEA transcription factor binding
GO:0008540 IEA proteasome regulatory particle, base subcomplex
GO:0030307 ISS positive regulation of cell growth
GO:0031398 ISS positive regulation of protein ubiquitination
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0032436 ISS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043409 ISS negative regulation of MAPK cascade
GO:0043518 ISS negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045111 IEA intermediate filament cytoskeleton
GO:0045737 ISS positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0070682 ISS proteasome regulatory particle assembly
GO:0090201 ISS negative regulation of release of cytochrome c from mitochondria

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000217958 PSMD10-001 protein_coding Homo_sapiens 0 965
ENST00000338548 PSMD10-003 retained_intron Homo_sapiens 0 309
ENST00000340200 PSMD10-006 protein_coding Homo_sapiens 0 660
ENST00000361815 PSMD10-002 protein_coding Homo_sapiens 0 617
ENST00000372295 PSMD10-004 protein_coding Homo_sapiens 0 503
ENST00000372296 PSMD10-005 protein_coding Homo_sapiens 0 313
ENST00000432890 PSMD10P2-001 processed_pseudogene Homo_sapiens 0 686
ENST00000436861 PSMD10P1-001 processed_pseudogene Homo_sapiens 0 662
ENST00000437000 PSMD10P3-001 processed_pseudogene Homo_sapiens 0 518
ENST00000553388 PSMD10-007 retained_intron Homo_sapiens 0 309

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